Maxalt Precautions and Warnings

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Maxalt Precautions and Warnings

Maxalt can interact with other medicines. It’s important for your doctor to know all of the medicines, dietary supplements, and over-the-counter medicines that you take with Maxalt. Use the migraine journal to keep a list of all medicines to share with your doctor. Only your doctor can prescribe prescription medicines for you. Do not stop taking any medicine without speaking to your doctor.

Do not take Maxalt if you:

  • Have had a serious allergic reaction to Maxalt or any of its ingredients
  • Have uncontrolled high blood pressure
  • Have heart disease or history of heart disease
  • Are currently taking monoamine oxidase (MAO) inhibitors such as Nardil (phenelzine sulfate) or Parnate (tranylcypromine sulfate) for clinical depression, or have taken MAO inhibitors within the last two weeks.

Because Maxalt may increase blood pressure, you should not take it if you have uncontrolled high blood pressure.

You should not use Maxalt within 24 hours of treatment with another 5-HT1 agonist (triptan-type drug), or an ergotamine-containing or ergot-type medication like dihydroergotamine or methysergide.

You should not take Maxalt if you have a hemiplegic migraine or basilar migraine.

You should not take Maxalt if you are hypersensitive to it or any of its inactive ingredients.


Maxalt and Serotonin Syndrome

Taking Maxalt with an SSRI (selective serotonin reuptake inhibitor — a class of antidepressants) or an SNRI (serotonin-norepinephrine reuptake inhibitor — another class of antidepressants) may cause a potentially life-threatening reaction called serotonin syndrome. Serotonin syndrome symptoms may include changes in your thinking, behavior, or level of alertness (such as agitation, hallucinations, coma), changes in your heart rate, blood pressure, or body temperature (such as fast heart beat, high or low blood pressure, fever), changes in your muscles and/or nervous system (such as sensitive reflexes, lack of coordination), and/or nausea, vomiting, and/or diarrhea.

Some SSRIs and SNRIs include:

  • Celexa (citalopram HBr)
  • Lexapro (escitalopram oxalate)
  • Paxil (paroxetine)
  • Prozac/Sarafem (fluoxetine)
  • Symbyax (olanzapine/fluoxetine)
  • Zoloft (sertraline)
  • Luvox (fluvoxamine)
  • Cymbalta (duloxetine)
  • Effexor (venlafaxine)


Learn more about Maxalt Drug Interactions


Maxalt and Drug Abuse and Dependence

There is no available information to suggest that Maxalt is associated with drug abuse or dependence.

Maxalt and Alcohol

There is little or no information regarding the effects of drinking alcoholic beverages while taking MAXALT.

Remember: Mixing alcohol and medicines puts you at risk for dangerous reactions. Protect yourself by avoiding alcohol if you are taking a medication and don’t know its effect. To learn more about a medicine and whether it will interact with alcohol, talk to your pharmacist or other health care provider.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010. Click the References Link below for a complete list of references.

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