Expert Opinion: Recent Genetic Research & Migraine

The exact cause of migraine is unknown but genetics is thought to play an important role. Migraines tend to run in families. A recent study, published on 6/12/11 in the British Journal Nature Genetics, helps confirm the role of genetics and inheritance in migraine. In this study, scientists uncovered 3 genes to be associated with migraine individuals and one of them exclusively linked to women with migraine. In this study, the genetic components (genome) of 23, 230 women were examined; 5122 had migraine. Differences in the genetic make-up (DNA) were evaluated and the 3 genes found linked to the women with migraine are:

1. PRDM 16

2. TRPM 8 (unique to women with migraine)

3. LRP1

This study helps to confirm earlier, smaller studies showing a genetic link to migraine. It is not expected that genetic testing will be part of the work-up for the majority of migraine individuals; however, this study is important is our understanding of the cause of migraine.

This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The Migraine.com team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.
View References

Comments

View Comments (14)

Poll