Midrin for Migraine: October, 2011, Update
If you’ve used Midrin or its equivalents as your Migraine abortive medication, you’ve probably followed the long saga of Midrin and medications equivalent to it being removed from the market. Thanks to one of our Migraine.com members, Mandy, I’ve learned that there may still be hope.
To summarize the situation, Midrin was developed long enough ago that it first went on the market before the current FDA drug approval process went into effect. During the many years between the time that the FDA approval process went info effect and the time that Midrin was discontinued, none of the pharmaceutical companies producing these medications did the required clinical trials and applied for FDA approval. So, first Midrin was discontinued, then the equivalent medications – medications with the same ingredients – were pulled from the market. Since Midrin was never approved by the FDA, there technically weren’t generics; there were equivalent drugs. For more background on this, including a copy of the email explanation I received from the FDA, see Looking for Midrin Equivalents for your Migraines?.
Mandy posted some comments on one of my other Midrin blog entries to let us know that her pharmacist has recently been able to get a Midrin equivalent medication for her. When I asked, she very helpfully provided the name of the manufacturer, Macoven Pharmaceuticals based in Magnolia, Texas.
This morning, I called Macoven’s customer service and spoke with a woman named Cindy. She confirmed that they are indeed producing and distributing a medication equivalent to Midrin. They distribute across the U.S., and pharmacists should be able to get their Isometh/Dich/Apap capsules. Those abbreviations stand for isometheptene mucate, dichloralphenazone, and acetaminophen
Cindy was well aware of the situation with these medications and the FDA. She told me that Macoven is “working with the FDA” to be able to keep their product on the market. Although I find this encouraging, I’m going to be cautious about being too encouraged until Macoven has officially worked things out with the FDA. The reason for my caution is that two other pharmaceutical companies have worked with the FDA over the last year to keep their products on the market, and they ended up discontinuing their Midrin equivalent medications.
I’ll be checking in with Macoven periodically to see what progress they’ve made with the FDA and will post updates whenever I have new information.