Frova Drug Interactions

FrovaDrug Interactions: an introduction

Frova may interact with other medicines. It is extremely important for you to tell your doctor about all the medicines you are currently taking, including your over-the-counter (non-prescription) medicines. The migraine journal can help you keep a list of all of your medicines. It is also important that you tell your doctor if you are taking any dietary supplements such as herbs or vitamins. Your doctor can best help you avoid any unpleasant side effects if he or she knows about everything that you are taking.

Drug Interactions with Frova

Frova Drug Interactions with Other Migraine Drugs:

Youshould not use other migraine drugs known as triptans within 24 hours after taking another triptan such as sumatriptan (Imitrex) or an ergotamine-containing drug such as Ergomar.

Taking these medications together can cause the blood vessels in the brainstem to constrict too much. Taking a triptan with an SSRI such as fluoxetine (Prozac) or an SNRI such as venlafaxine (Effexor), can cause potentially life-threatening serotonin syndrome.


Taking Frova and Antidepressants:

You should not take Frova if you take an MAO inhibitor (monoamine oxidase inhibitor–a class of antidepressants) or are within 2 weeks of stopping an MAO inhibitor.

Before using Frova, tell your doctor if you are also taking an antidepressant such as:

  • Celexa (citalopram)
  • Cymbalta (duloxetine)
  • Lexapro (escitalopram)
  • Prozac, Sarafem (fluoxetine)
  • Luvox (fluvoxamine)
  • Paxil (paroxetine)
  • Zoloft (sertraline)
  • Effexor (venlafaxine)

Taking Frova with an SSRI (selective serotonin reuptake inhibitor — a class of antidepressants) or an SNRI (serotonin-norepinephrine reuptake inhibitor — a class of antidepressants) may cause a potentially life-threatening reaction called serotonin syndrome. Serotonin syndrome symptoms may include changes in your thinking, behavior, or level of alertness (such as agitation, hallucinations, coma), changes in your heart rate, blood pressure, or body temperature (such as fast heart beat, high or low blood pressure, fever), changes in your muscles and/or nervous system (such as sensitive reflexes, lack of coordination), and/or nausea, vomiting, and/or diarrhea.


Frova and Propranolol:

Propranolol (a drug used to treat high blood pressure) may raise blood levels of Frova and increase your risk of experiencing side effects of Frova.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010. Click the References Link below for a complete list of references.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010.
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