Frova Special Warnings

Frova and Overuse:

Using Frova two or more days a week for more than 3 months can cause medication-overuse headache (a “rebound headache”). Medication-overuse headaches cause a dull or migraine-like headache that is present at least 15 days per month. You can prevent medication-overuse headache by not using Frova or other migraine medications) as often (per attack, per week, and per month) and starting preventive treatment when necessary.

By keeping a migraine journal of what doses of Frova you are taking when you experience a migraine, you can be prepared to discuss with your doctor whether you might be experiencing overuse headaches. Be sure to share your headache log with your doctor at your next appointment.


Frova and Blood Pressure:

Frova has been reported to raise blood pressure on rare occasions in people with and without high blood pressure. If you have uncontrolled high blood pressure you should not use Frova.

What is your blood pressure? Keeping a blood pressure log if you have been diagnosed with high blood pressure is a very good way to be prepared to speak with your physician and be aware of any changes in your condition.

Special Warning: Frova and Heart Disease:

Although extremely rare, serious heart problems, including some that have been fatal, have occurred after taking triptans like Frova. These problems have occurred most often in people with risk factors for heart disease. Risk factors include:

  • Coronary artery vasospasm (blood vessels constricting in the heart)
  • Stroke
  • Heart attack
  • Rapid heart rate
  • Irregular heart rate

You should not take Frova if you have heart disease risk factors including:

  • High blood pressure
  • High cholesterol
  • Smoking
  • Being obese
  • Diabetes
  • Strong family history of heart disease
  • Menopause
  • Male over 40 years of age

If you have any of these conditions or if any of these circumstances describe you, have your doctor evaluate your heart and physical condition to determine if you are reasonably free of heart disease and risk of stroke, before taking Frova.

If you do have risk factors and your doctor decides you can take Frova, it is strongly recommended that you take your first dose of Frova in your doctor’s office or a similar setting with medical staff present unless you have previously taken Frova.

Because stroke can occur, your doctor may choose to do an electrocardiogram (ECG) immediately following a dose of Frova if you have heart disease risk factors.


What should you do if you experience possible cardiac symptoms while taking Frova?

If you feel shortness of breath, heart throbbing, persistent pain, tightness or pressure in the chest or throat shortly after taking Frova, call your doctor right away.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010. Click the References Link below for a complete list of references.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010.
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