Maxalt Side Effects

Maxalt Side Effects: an introduction

As with any medicine, Maxalt can cause side effects. Generally, Maxalt is tolerated well by most people. Even when taking different doses, most of the Maxalt side effects are mild, don’t last long, and cause no lasting problems. Maxalt can cause rare but serious side effects involving your heart, including heart attack or stroke. Before using Maxalt, tell your doctor about any:

  • Past or present medical problems
  • History of high blood pressure, chest pain, shortness of breath, heart disease, or stroke
  • Risk factors for heart disease or blood vessel disease including:
    • High blood pressure
    • Diabetes
    • High cholesterol
    • Obesity
    • Smoking
    • Family history of heart disease
    • Family history of blood vessel disease
    • Post menopausal
    • Male over age 40
    • Allergies you have or have had

Also tell your doctor if you are:

  • Pregnant or plan to become pregnant
  • Breastfeeding or plan to nurse your baby

If any of these apply to you, you may not be able to take Maxalt, or you may need to have your dose adjusted or have special tests to safely use Maxalt.

Maxalt Side Effects (Tablets and Oral Disintegrating Tablets)

Both forms of Maxalt are generally well tolerated. Side effects are typically mild and didn’t last long. The number of side effects experienced in clinical trials did not increase when people took up to three doses within 24 hours. Side effects were no more frequent when people were taking other drugs that help to prevent migraine, such as birth control pills, propranolol and pain killers. Side effects were not affected by age or gender.


Maxalt Side Effects

Side effects of Maxalt may change depending on the dose you take. The side effects listed below were experienced by 2% or more patients in Maxalt clinical trials for migraine.


Maxalt Side Effect


5 mg


10 mg



Atypical (unusual) sensations 4% 5% 4%
Skin tingling or numbness 3% 4% <2%
Pain and other pressure sensations 6% 9% 3%
Chest pain: tightness/pressure and/or heaviness <2% 3% 1%
Neck/throat/jaw: pain/tightness/pressure <2% 2% 1%
Regional pain: tightness/pressure/heaviness <1% 2% 0%
Pain in an unspecified location 3% 3% <2%
Digestive issues 9% 13% 8%
Dry mouth 3% 3% 1%
Nausea 4% 6% 4%
Neurological issues 14% 20% 11%
Dizziness 4% 9% 5%
Headache <2% 2% <1%
Sleepiness 4% 8% 4%
Other issues
Weakness/fatigue 4% 7% 2%

Have you experienced side effects using Maxalt?

You are encouraged to report your side effects of any prescription medicines to the Food and Drug Administration (FDA). If you would like to report your side effects while taking Maxalt, visit, or call 1-800-FDA-1088.

We encourage you to visit the Maxalt forum. There you can learn from others’ experiences with Maxalt. And of course, sharing your story might help others like you to learn about the potential benefits and risks of taking Maxalt.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010. Click the References Link below for a complete list of references.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010.
View References