MigreLief is the brand name for a supplement that combines the natural products feverfew, magnesium and riboflavin. MigreLief was formerly called MigraHealth and MigreLieve.

MigreLief comes in tablet form.

A 2003 study in the Journal of the American Nutraceutical Association said that the combination of the natural migraine remedies may have an increased benefit. Feverfew, magnesium and riboflavin used together, the study said, might help keep the blood flowing properly in the brain. If blood is flowing appropriately it may prevent sudden spasms and decrease inflammation, thus preventing migraines.

Information on the ingredients in MigreLief


Feverfew, a plant, is believed to help migraines because it is thought to relieve smooth muscle spasms, stop the brain’s blood vessels from contracting and prevent inflammation.


Magnesium is a mineral, the fourth most abundant mineral in the body. Some studies have shown low magnesium levels in the brain magnesium during migraine attacks and magnesium is also needed for proper nerve function.


Riboflavin is a vitamin that is also known as Vitamin B2. It is necessary for growth and red blood cell production.

Possible side effects and other precautions

For detailed information on side effects and other warnings, please see the individual pages for feverfew, magnesium and riboflavin.

The manufacturer of MigreLief says side effects include:

  • Mild upset stomach (if stomach pain occurs, for those taking a calcium and magnesium supplement, should change to calcium only)
  • Loose stools
  • Bright yellow urine, which is safe and caused by the Vitamin B2

Who should not take MigreLief

For specific information on who shouldn’t take the separate ingredients in MigreLief, please go to the individual pages for feverfew, magnesium and riboflavin.

The manufacturer of MigreLief says the product should not be taken by:

  • Pregnant women or women who are breastfeeding
  • Children under age 2
  • People taking potassium-sparing diuretics
  • People with kidney failure



As always, the best source for advice on treating your migraines is your own migraine specialist. These descriptions of natural remedies are provided only for informational purposes. You should begin no medication or supplement without first checking with your physician. Again, this information should in no way substitute or be mistaken for medical advice.

Written by: Otesa Miles | Last review date: November 2010
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