Inderal LA Precautions and Warnings

Inderal LA and other medicines containing propranolol can interact with other medicines. It’s important to know all of the medicines, dietary supplements, and over-the-counter medicines that are being taken with Inderal LA. Use the migraine journal to keep a list of all of your current medicines to share with your doctor at your appointments. Only your doctor can prescribe prescription medicines such as Inderal LA for you. Do not stop taking any prescribed medicine without your doctor’s approval. Especially do not suddenly stop taking Inderal LA or another form of propranolol because this can lead to dangerous side effects such as worsening chest pain or even a heart attack.


You should not take Inderal LA if you have:

  • Asthma
  • An unusually slow heart rate (heart block)
  • An allergy to Inderal LA, propranolol (its active ingredient), or any of its other components. Taking Inderal LA may cause an allergic reaction such as hives, peeling skin, a rash, and/or difficulty breathing, or a body-wide allergic reaction known as Stevens-Johnson Syndrome.


You should use Inderal LA with caution if you have:

  • Asthma or another type of breathing problem such as chronic bronchitis or emphysema (both of these are forms of chronic obstructive pulmonary disease or COPD)
  • Heart failure
  • Diabetes (Inderal LA may make it more difficult to notice the signs of low blood sugar, such as changes in heart rate or blood pressure.)
  • Decreased kidney or liver function
  • Symptoms of a high blood pressure emergency (when blood pressure is more than 180/120 mm Hg and damage to organs such as the eyes or kidneys has occurred)
  • Thyroid disease or overactive thyroid (hyperthyroidism)
  • Glaucoma (a condition in which there is too much pressure inside of the eye) Inderal LA may cause your glaucoma test results to be less accurate because it may affect eye pressure. If you stop taking Inderal LA, this may improve. Still, never stop taking a prescribed medicine without your doctor’s approval and guidance. Stopping Inderal LA suddenly can cause an increase in chest pain or sometimes a heart attack.
  • A history of severe allergic reaction (If you have severe allergies, it may be more difficult to treat you if you develop an allergic reaction to Inderal LA.)

Inderal LA Use in Children:

The safety and effectiveness of Inderal LA use in children has not been established. Some children who have taken propranolol (the active ingredient in Inderal LA) have developed asthma and/or congestive heart failure (when the heart is unable to pump enough blood to the body).

Inderal LA Use in Elderly Patients:

There were not enough older adults participating in propranolol studies for experts to learn whether Inderal LA might affect older adults differently or cause different side effects than it does when used by adults under the age of age 65. However, elderly patients are more likely to have other medical conditions that may increase the risk of adverse effects of Inderal LA, including:

  • Kidney problems or decreased kidney function
  • Liver problems or decreased liver function
  • Heart problems or decreased heart function
  • Other health conditions

For this reason, if you are 65 or older and your doctor decides to prescribe Inderal LA for your high blood pressure, chest pain, or migraine attacks, he or she should start you on a low dose of propranolol (the active ingredient in Inderal LA) and carefully monitor your reaction to it.


Inderal LA and Alcohol

It is recommended that you avoid using alcohol when taking Inderal LA or another form of propranolol. Alcohol boosts the levels of propranolol in your bloodstream. Drinking alcohol while taking the propranolol in Inderal LA can cause serious side effects, such as dangerously low blood pressure or sedation (falling asleep).

Remember: Mixing alcohol and medicines such as Inderal LA puts you at risk for adverse reactions and dangerous side effects. Protect yourself by avoiding alcohol if you are taking a medication such as Inderal LA and don’t know its effect. To learn more about a medicine and whether it will interact with alcohol, talk to your pharmacist or other health care provider.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010. Click the References Link below for a complete list of references.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010.
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