Relpax Drug Interactions

Relpax Drug Interactions: an introduction

Relpax may interact with other medicines. It is very important for you to tell your doctor about all the medicines you are currently taking, including your over-the-counter (non-prescription) medicines. The migraine journal can help you keep a list of all of your medicines. It is also important that you tell your doctor if you are taking any dietary supplements such as herbs or vitamins. Your doctor can best help you avoid any unpleasant side effects if he or she knows about everything that you are taking.


Relpax Drug Interaction with Other Migraine Medicines

Relpax should not be used within 24 hours after taking other headache drugs. These include those containing triptans and ergot related drugs such as:

These medicines have side effects similar to Relpax and could cause your blood vessels to constrict too much.

Relpax Drug Interaction with Antidepressants

Your doctor needs to know if you are taking selective serotonin reuptake inhibitors (SSRIs) or serotonin norepinephrine reuptake inhibitors (SNRIs), two types of drugs for depression or other disorders. Common SSRIs are:

  • Celexa (citalopram HBr)
  • Lexapro (escitalopram oxalate)
  • Paxil (paroxetine)
  • Prozac/Sarafem (fluoxetine)
  • Symbyax (olanzapine/fluoxetine)
  • Zoloft (sertraline
  • Luvox (fluvoxamine)

Common SNRIs are:

  • Cymbalta (duloxetine)
  • Effexor (venlafaxine)

Taking Relpax with an SSRI (selective serotonin reuptake inhibitor — a class of antidepressants) or an SNRI (serotonin-norepinephrine reuptake inhibitor — a class of antidepressants) may cause a potentially life-threatening reaction called serotonin syndrome. Serotonin syndrome symptoms may include:

  • Changes in your thinking, behavior or level of alertness (such as agitation, hallucinations, coma)
  • Changes in your heart rate, blood pressure or body temperature (such as fast heart beat, high or low blood pressure, fever)
  • Changes in your muscles and/or nervous system (such as sensitive reflexes, lack of coordination)
  • Nausea, vomiting, and/or diarrhea


Relpax Drug Interactions with Other Drugs

Relpax should not be used within 72 hours of taking these medications. Tell your doctor if you have taken the following medicines within the past 72 hours:

  • Nizoral (ketoconazole)
  • Sporanox (itraconazole)
  • Serzone (nefazodone)
  • TAO (troleandomycin)
  • Biaxin (clarithromycin)
  • Norvir (ritonavir)
  • Viracept (nelfinavir)

These medicines may cause an increase in the amount of Relpax in the blood.


Relpax and MAO — Inhibitors

An interaction between Relpax and a MAO-I is not expected to occur.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010. Click the References Link below for a complete list of references.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010.
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