Relpax Side Effects

Relpax Side Effects: an introduction

As with any medicine, Relpax can cause side effects. Generally, Relpax is tolerated well by most people. Even when taking different doses, most of the Relpax side effects are mild, don’t last long and cause no lasting problems. However, Relpax can cause extremely rare but serious side effects involving your heart, including heart attack or stroke. These types of problems have generally occurred in people who already had coronary artery disease when they took the drug.

Before you use Relpax, tell your doctor if you have:

  • Uncontrolled high blood pressure
  • Heart disease or a history of heart disease
  • Hemiplegic migraine or basilar migraine (if you are not sure about this, ask your doctor).
  • (Or had) a stroke or problems with your blood circulation
  • Serious liver problems

Also, be sure to tell your doctor if you have heart disease risk factors including:

  • Diabetes
  • Menopause
  • Smoking
  • Being overweight
  • High cholesterol
  • A family history of heart disease
  • Being over 40 and a man
  • Being a woman who has had a hysterectomy

If you have any of these conditions, you may need to have your dose adjusted or have special tests to safely use Relpax.

Side effects of Relpax may change depending on the dose you take. The side effects listed in the three tables below were experienced by 2% or more patients in very large worldwide Relpax clinical trials for migraine.

Relpax Side Effects (Tablets)

Across all doses, most adverse reactions were mild and didn’t last long. The frequency of side effects in clinical trials did not increase when up to 2 doses of Relpax were taken within 24 hours. Side effects were not affected by gender, age, or race of the patients.

Side Effect


Relpax 20 mg

Relpax 40 mg

Relpax 80 mg

Tingling sensations 2% 3% 3% 4%
Feeling warm 2% 2% 2% 2%
Chest tightness/pain/pressure 1% 1% 2% 4%
Abdominal pain/discomfort/stomach pain/cramps/pressure 1% 1% 2% 2%
Dry mouth 2% 2% 3% 4%
Indigestion 1% 1% 2% 2%
Tight throat/difficulty swallowing 0.2% 1% 2% 2%
Nausea 5% 4% 5% 8%
Dizziness 3% 3% 6% 7%
Sleepiness 4% 3% 6% 7%
Headache 3% 4% 3% 4%
Body weakness 3% 4% 5% 10%


Have you experienced side effects using Relpax?

You are encouraged to report your side effects of any prescription medicines to the Food and Drug Administration (FDA). If you would like to report your side effects while taking Relpax, visit, or call 1-800-FDA-1088.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010. Click the References Link below for a complete list of references.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010.
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