Topamax Uses


Topamax is used:

  • To prevent migraine headaches in adults. (Topamax is not intended to relieve the pain of a migraine headache once it has started.)
  • As a first-line single-drug treatment to prevent partial seizures and tonic-clonic seizures in people aged 10 and older who have epilepsy
  • In combination with other drugs to prevent partial seizures or tonic-clonic seizures in people aged 2 and older who have epilepsy
  • In combination with other drugs to prevent seizures in patients aged 2 and older with Lennox-Gastaut syndrome (a severe form of epilepsy)



A migraine is typically described as a headache disorder that causes symptoms beyond what might be considered normal, including throbbing, nausea, and sensitivity to light, sound, and/or odors. Topamax is only used to prevent migraine attacks. It does not work to treat the pain of a migraine that has already begun.



is a condition that affects the brain. In epilepsy, sometimes some of the nerve cells in the brain “fire” or “turn on” when they are not supposed to. This interrupts normal brain function, causing symptoms such as strange sensations, emotions, and actions, including seizures. When a person has a seizure, they may have muscle spasms, convulsions (violent shaking), and sometimes a loss of consciousness.

There are many types of seizures. They are given different names based upon how much of the brain they affect and what part of the brain they target. Topamax is used to prevent several types of seizures, including partial seizures, tonic-clonic seizures, and seizures associated with Lennox-Gastaut Syndrome.

Partial seizures.

These are seizures that affect only one side of the brain. They can last anywhere from 90 seconds to 2 minutes. People who have partial seizures sometimes stay conscious (awake and alert) during the seizure, while others do not.


Tonic-clonic seizures.

This type of seizure used to be known as grand mal seizures. These seizures typically include loss of consciousness. In this type of seizure, the body’s muscles first stiffen and later go into spasms.


Lennox-Gastaut Syndrome.

This is a severe form of epilepsy that starts in early childhood and causes symptoms including frequent seizures of different types, as well as delays in learning and problems interacting with other people. The seizures related to Lennox-Gastaut Syndrome can cause stiffening of the muscles, falling and loss of consciousness, staring spells, or sudden muscle spasms

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010. Click the References Link below for a complete list of references.