Ultram (tramadol) Side Effects

As with any medicine, Ultram can cause side effects. Generally, Ultram is tolerated well by most people; however certain people may not be able to safely use Ultram because they have certain medical conditions.

COMMON ULTRAM SIDE EFFECTS

The most common reported side effects that occurred in more than 5% of patients who took Ultram that are stated in the manufacturer Prescribing Information were in the central nervous system and gastrointestinal system and are:

  • Dizziness/vertigo
  • Nausea
  • Constipation
  • Headache
  • Sleepiness
  • Vomiting
  • Severe itching
  • CNS Stimulation (speeding up mentally and physically)
  • Weakness
  • Sweating
  • Indigestion
  • Dry Mouth
  • Diarrhea

 

COMMON ULTRAM ER SIDE EFFECTS

The most common reported side effects that occurred in more than 5% of patients who took Ultram ER and are stated in the manufacturer Prescribing Information are:

  • Dizziness (not vertigo)
  • Nausea
  • Constipation
  • Headache
  • Sleepiness
  • Flushing
  • Severe itching
  • Vomiting
  • Insomnia
  • Dry Mouth
  • Diarrhea
  • Weakness
  • Drop in blood pressure when you stand up after sitting
  • Increased sweating
  • Loss of appetite

 

Ultram Side Effects

Side effects of Ultram may change depending on the dose you take. The side effects listed in the 2 tables below were experienced by 5% or more of the people in the Ultram clinical trials for pain.

Most Common Side Effects of Ultram

Side Effect up to 7 days Up to 30 days Up to 90 days
Dizziness/Vertigo 26% 31% 33%
Nausea 24% 34% 40%
Constipation 24% 38% 46%
Headache 18% 26% 32%
Sleepiness 16% 23% 25%
Vomiting 9% 13% 17%
Severe itching 8% 10% 11%
CNS Stimulation(speeding up mentally and physically 7% 11% 14%
Weakness 6% 11% 12%
Increased sweating 6% 7% 9%
Indigestion 5% 9% 13%
Dry Mouth 5% 9% 10%
Diarrhea 5% 6% 10%

 

Have you experienced side effects using Ultram? You are encouraged to report your side effects of any prescription drugs to the FDA (Food and Drug Administration). If you would like to report your side effects while taking Ultram, visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Ultram ER Side Effects

Side effects reported in greater than 5% of the Ultram ER

patients, and that were more common in Ultram ER- than placebo-treated patients, are listed below.

Most Common Side Effects of Ultram ER

Side Effect Ultram ER

100 mg

Ultram ER

200 mg

Ultram ER

300 mg

Ultram ER

400 mg

Placebo
Dizziness(not vertigo) 15.9% 20.3% 22.5% 28.2% 6.9%
Nausea 15.1% 22.5% 25.5% 26.2% 7.9%
Constipation 12.2% 17% 21.3% 29.7% 4.2%
Headache 12.2% 15.5% 11.5% 15.8% 10.6%
Sleepiness 8.2% 11.3% 7.3% 20.3% 1.7%
Flushing 7.7% 10% 8.8% 15.8% 4.4%
Severe itching 6.2% 8.5% 7.5% 11.9% 1%
Vomiting 5% 7.3% 8.5% 9.4% 2.7%
Insomnia 6.5 8% 9% 10.9% 3.2%
Dry Mouth 5% 7.3% 9.8% 8.9% 1.5%
Diarrhea 3.7% 6.8% 8.5% 5% 4.2%
Weakness 3.5% 6% 6.5% 6.4% 1.7%
Drop in blood pressure when you stand after sitting 1.7% 4.3% 2% 5.4% 2.2%
Increased sweating 1.5% 2% 3.8% 6.4% 0.2%
Loss of appetite 0.7% 1.8% 5.3% 5.9% 0.2

 

Have you experienced side effects using Ultram ER? You are encouraged to report your side effects of any prescription drugs to the FDA (Food and Drug Administration). If you would like to report your side effects while taking Ultram, visit www.fda.gov/medwatch, or call 1-800-FDA-1088.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010. Click the References Link below for a complete list of references.

Written & reviewed by: Lisa Erwin R.Ph. CGP | Last review date: Dec 2010.
View References