I have had debilitating migraines for over 25 years. I have tried EVERY type of migraine medication– hoping each time the new one would work- and would be so frustrated every time. I previously thought my migraines were hormone related, but have now realized they are also caused by changes in the weather/ air pressure. My neurologist has tried many medications, and finally Cambia! Cambia is by far the best thing I have used- If I can take it as soon as I feel the migraine coming on, it works great! I have been taking it for 6 months, and only a couple of times it didn’t work. I also started taking 400mg of magnesium glycinate every day 6 months ago as well and I feel it has also helped in migraine prevention. Make sure you get the GLYCINATE form of magnesium. Hope this helps others as much as it has helped me! I am so thankful my migraines are finally less frequent and manageable!