I was just diagnosed with undifferentiated connective issue disorder. Initially I was started on 200 mg of Plaqueil, but
my rheumy just raised it to 400 mg. I’m finding that when I take it all at night, I’m waking up every morning with a
migraine and nausea. I’m going to try splitting the dose – 200 mg in the morning and 200 mg at night and see if that
helps. The Plaquenil is helping – it took me several years to get diagnosed. There had been weekends when I couldn’t even get out of bed because of exhaustion and now I’m able to do what I want, so I don’t want to stop it.
Has anyone had a similar experience with Plaquenil? How did you manage it?