My 12 year old daughter is taking daily preventive Amatryptalene and Imitrex for abortive treatment. She still needs to take two imitrex a week even on the preventive. I’m running out of money! Paying $450 for 12 doses of Summatriptan Nasal Spray. I want to try Excedrin Migriane for her. I talked to the pharmy and he didn’t think the aspirin was a huge risk at her age for Reyes but said I should consult her pediatrician. He said there is no drug interaction with both meds but it’s the aspirin that is the risk. The doctor office recommends her not taking it. They say an Advil plus caffeinated beverage would be more preferred but we’ve tried that and it works to a degree. Takes the edge off but not always completely. What if Excedrin really works for her? How bad is taking it like once a week as far as the risk involved regarding aspirin at her age. I grew up taking baby aspirin all the time. If she can only take two abortive meds a week in order to avoid MOH, we opt for summatriptan b/c it works. But if Excedrin works too we could use it half the time and save A LOT of money.