Forums


Medications & Prescription Treatment

Have a bad reaction to any of these prescriptions?

  • By Brian in TN

    Alprenolol, Detrol, lidocaine, propranolol, amitriptyline, dextromethorphan, MDMA, Reglan, amphetamines, diphenhydramine, metoclopramideprolol, risperidone, aripiprazole, donepezil, metoprolol, Rythmol, atomoxetine, doxepin, mexiletine, Sertraline, benztropine, duloxetine, mirtazapine, tamoxifen (p), Bystolic, Ecstasy, nebivolol, thioridazine, carvedilol, encainide, nortripyline, timolol, chlorpheniramine, flecainide, ondansetron, tolterodine, chlorpromazine, fluoxetine, oxycodone, tramadol, clomipramine, fluvoxamine, paroxetine, venlafaxine, clonidine, haloperidol, perphenazine, zuclopenthixol, codeine(p), hydrocodone (p), promethazine, desipramine, imipramine, or propafenone? All of these substances, many of which are prescribed for migraine disease are metabolized through Cytochrome P450 2D6 which for many people may not perform in a predictable manner. This has been found by Australian researchers to be very clearly associated with young men who are being treated for depression when they commit out of character violent crimes. My mother and I have both had bad reactions to several of these drugs so I plan on discussing this with my doctors. A website I found: http://youscript.com/healthcare-professionals/what-is-youscript/pharmacogenetic-testing/cytochrome-p450-2d6-genotyping/ provides genetic testing to determine whether you have a genetic anomaly that affects your ability to metabolize these drugs.

    Reply Created with Sketch. reply
  • By Brian in TN

    I had to copy those drugs from a table and then install commas and spaces to make it readable (barely) so if adding a letter to any of those creates a match to a drug you’ve had problems with I recommend you visit the website and click on the Metabolism tab half way down the page.

    Reply Created with Sketch. reply