Does anyone have experience (positive or negative) with Namenda? I just changed doctors and the new one ( headache specialist) seems so much better then the last. He’s taking me off topamax which hasn’t been as beneficial as it could have been (maybe cut down the intensity but of that I can’t be sure). I started the namenda a week ago and am hopeful I’m seeing a difference, although I had to leave work cause a wicked migraine. Please let me know if you have any experience with this drug, as I don’t think it’s commonly used but is being used more now for chronic migraine. Thanks. Laurie
I trialed Namenda several months ago. Unfortunately it didn’t work for me. There is more to the story in my case however…
I have a condition called Dystonia that is a movement disorder caused by a problem in a specific part of the brain called the basal ganglia. As a result, Dystonia reacts quite badly to particular meds that work within the brain. Namenda is one of them. Because of side effects due to my Dystonia, I really wasn’t able to trial the Namenda as we had hoped. I tried it three times, praying we could figure out a way to make it work. The drug information didn’t at that point mention the problem, so it caught me quite off guard.
That said, when I had a discussion with my headache specialist, she mentioned that Namenda has a really good side effect profile, and is especially good with Migraine with aura. We really thought it was worth trying. Many docs are catching on and giving it a go with their patients, and many are successful.
I hope you have luck with Namenda. Remember that a first try may result in some side effects that a second, slower try may make easier for you. So many patients give up so quickly, when often it is just an alteration in HOW the trial is done that turns a miserable failure into a life changing success.
After many many various drugs by other neurologist, the new neurologist has given me Namenda at 20 mg/day. It has been <2 weeks, yet my headaches are down by 80%. I feel great and happy.
I am also taking 1800 mg/day of Gabapentine and perhaps it is also contributing to the better response.
Will update this post in a few weeks and if the trends continues, I will provide his name so others can benefit.
I have been on Namenda for almost three years. I take 5 mg in the AM and 5 mg in the PM. I am taking it for off-label use treating OCD. It has improved my quality of life in regards to OCD immensely. The dose was increased once and it made me terribly ill. I had no idea it was being used for migraines until just now. I obviously still have migraines while taking it but maybe I never got up to a therapeutic dose for migraines. Maybe it has helped my migraines not be even worse, though. Amazing how many conditions one medication can be used for!
I couldn’t tolerate the 20 mg dose either. It made me feel very ill and disoriented. The 10 mg dose works fine for me with no side effects. I’m glad I’m not alone in not being able to handle the increased dose. 😊
Neil Raskin, M.D.
Neurologist and headache specialist at University of California @ San Francisco. is the doctor who is treating me. Although headaches continue, I am about 30% better now than I was before the new treatment. Much like the rest of us who get a lot of recommendations from our friends and family, I broke down and have had a few sessions of acupuncture with no noticeable improvement.
I am starting my second week of trial with Namenda XR. My nagging daily pain is easing. I have a great deal of difficulty with neck pain and am currently seeking the help of a chiropractor, however, at twenty dollars a visit, on Disability, I am unable to see him as often as I need to in order to truly address the problem. One day at a time, I am hopeful for a much better year in 2016, because this year has been a rough one. I will also get my botox injections the first week of the year with an increase in dosage. I would truly be happy to have three whole days without pain, that would be awesome.
I was prescribed this drug by the UCSF Headache Center which my local neurologist referred me to. Very happy with this drug! I have tried a long list of supposed migraine prophalytic drugs over the last 15 years but none have worked for me. Memantine is a game changer for me. I started at 5 mg and titrated up to 10 mg after a week. I very quickly began to see an effect with the 10 mg. The frequency of headaches was greatly reduced and even the ones I did have were much milder sometimes to the point that I didn’t have to use my usual triptan. I am now at 15 mg for the last few weeks to see if I can get any further improvement. I have gone from having ~12 headaches a month to around 4 mild ones very quickly. I have no side effects that are apparent to me- a little burning in my legs for a few days when I increase the dose.
What other preventatives have you tried?I have been using Amitriptyline 50mg for the past 8 months but for the past 3 months my headache frequency has increased and as well as intensity. My Neurologist is increasing my dosage another 30mg. Prior to this I have tried Topamax and Nortriptyline without success. If the increased dosage doesn’t work my next med will be Namenda. I’m also curious about side effects if you have any.
I just realized how old this thread is but I have been on and off Namenda for migraines for the past year. It seems to work well for my migraines. But even at 5mg twice a day I feel completely wrung out and have momuof complete confusion. I am 65 years old and also take 100mg of Topamax twice a day for the past year. Other than losing weight the Topamax has been tolerated pretty well. I went off the Namenda in May had headaches come back almost daily so just started back up 2 weeks ago. I see neurologist again early October. I just am so weak and tired on the Namenda. I blamed the Topamax but it’s definitely the Namenda I know that now after a few months off. Anyone else have problems with this?