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Topiramate withdrawal

  • By vitamin_migraine

    Hi!

    I recently had to stop topiramate after 6 months of use. Although it was effective, I had lost 20lbs and dropped down to 100lbs (5’7″) and became essentially unable to study or work because of vocabulary and memory loss as well as fatigue. I was so out of it I just thought I was depressed but when I consulted I was immediately tapered off. As I had a previous intoxication to Lamictal (rare) and experience violent hallucinations and/or vertigo from any kind of new or old generation antidepressants, toxicology and internal medicine were consulted and they believe I’m not capable of metabolizing most medications (although I have kept the Lyrica, this seems to be fine).

    My question is then a bit complex. I suffer severe status migrainus of hemiplegic AND basilar type that can last up to two weeks *with* daily oral prednisone AND twice weekly IV decadron (they now treat me with ergots in the ER). They once thought I had epilepsy as I have had 3 concussions from fainting.

    I know paresthesia is supposed to be common on topamax. I never experienced this, in fact, it helped with my hemiplegia. After a week and a half of no more topiramate, NOW I’m experiencing the most constant falling asleep in my feet, legs, hands, arms and back. My legs were also so weak today I was not capable of walking at one point and felt on the verge of falling many times today. So is this topiramate withdrawal?? Or just another migraine and I just forgot what it was like for two months? I just spent 2 full days in the hospital last week getting investigated for all these medicine intolerances and I’m not going back unless I have to, but I’m still groggy enough to not be sure what is normal (although much much more alert, enough to join this community!).

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  • By Nancy Harris Bonk Moderator

    Hi there,

    I’m happy to hear you feel alert enough and able to join us here in the Migraine.com discussion forum. Welcome!

    The symptoms you describe could very well be associated with migraine, but the only way to tell is to discuss them with your doctor. Are these they type of symptoms you had before you were taking Topamax? By any chance did you mention these issues to the doctor in the hospital and did they have anything to say about them?

    Sorry for more questions then answers!! Hang in there.

    I’m not sure if you are aware of this or not but sustaining a traumatic brain injury or concussion, can make migraine more difficult to treat. Here is information on migraine and concussion; https://migraine.com/blog/migraine-and-concussion/.

    Nancy

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  • By Teania

    I never had all of that, I had the tingling in my hands and feet when I was on the Topamax but it went away after just two days without the pill. Instead I had migraines from taking the Topamax. And now that I’ve stopped, though I did it without a doctor’s consent, I just couldn’t take it anymore. I am getting migraines all the time. Mostly before I fall asleep or when I just wake up and they seem to last longer since my Imitrex doesn’t take care of it in the same time frame. So I’ve taken to chasing it with Tylenol, but only about 162.5 mg’s of Tylenol, which is half a pill.

    I am no getting more depressed and tired and I just am starting to hate my migraines more and more. It’s like it’s just a constant pain.

    I fear that going cold turkey or just taking Topamax all together has given me a violent push into having Chronic Migraines as opposed to me having only episodic migraines…

    Is that possible?

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  • By Morning

    Hi there:
    I see that this was posted back in march so hopefully you will still get to read this, but I hated Topamax. It changed the taste of food, made me feel numb/pins and needles in my arms and legs, sleepy and more. However I did get a few less of my migraine attacks, but the ones I did get I couldn’t control them. I was in so much pain and throwing up ALL day. This wasn’t normal for me either. I felt like the migraines I usually had day to day were put in a jar and a few times a month someone opened the jar and boom they all exploded with pain, throwing up, diarrhea, and more. I asked the Dr. the same question you asked and they said it could have just been a bad time in my migraine cycle. But I know my body and it didn’t feel right so after 3 months I got off of the meds. Now these meds may help other ppl but it didn’t work for me. I am sorry for your suffering. I am trying to deal with my migraines as well. Hopefully you and your Dr will come up with the right meds that work for you.

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  • By Lynn Voedisch

    I see that this is an old topic, hope someone comes over here to read it. I’ve been going off Trokendki (which is just a fast-acting form of Topamax) through a long process of weaning down. I was on 200 mg. and now am at 25 mg. and looking at the end next week–-just in time for Christmas. The problems I am having are awful. While unlike Angstar, I took very well to Topamax and it let me lead a migraine-free life for several years, it just went out of control and my dosages became dangerous. Then the loss of memory, damage to my kidneys. And with the switch to Trokendi, hair loss.

    Anyway coming down has been way worse than going up. I get dizzy, nauseated, no appetite, my IBS (which I recently soothed with a gluten-free diet) came roaring back, my vision is fuzzy at times, I have no energy, and a general flu-like feeling. I also am getting many more headaches than usual. usually overnight. And like the very first poster, I have had my leg and arm fall asleep. Very scary. It’s really bad the first few days after the step down, then I tend to get used to it…until the next step down. I’m really worried about that last step down and off and even am putting it off until after Christmas, so I can enjoy the holiday.
    Does anyone know how long the withdrawal lasts? I’ve been going through this for over a month and nearly losing my mind.
    My doctor does have me starting up on Namenda, and we hope that will start working on the migraines There is a very short list of side effects for that drug.
    But I’m really about to lose it and even decided to just get gift cards for the last remaining people on my Christmas list because I just can’t tolerate the stress of shopping.

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  • By Katie M. Golden Moderator

    Lynnv,
    last year I had to come off of Topamax due to hair loss after I had been on it for years. Like you, the withdrawal process was excruciating. I’m wondering if you cut the doses too quickly, which is different for everyone. Although I’m not a doctor, I don’t see any harm in staying at 25mg through the holidays. This can also give your body a chance to get used to the Named which may help your withdrawal symptoms.
    -Katie

    Sadly in the end, I just had to push through it. Eventually my body returned to normal, or as normal as its ever going to be.

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  • By Lynn Voedisch

    Well, I’m coming down the way my doctor wants me to come down, so I can’t say I’m doing it too fast. At first he wanted me to go down by 50mg. At a time and my body couldn’t handle it.

    I have some extras to use at the very end, which is why I’ll go through Christmas okay. But there’s not enough for New Year’s. I was thinking of getting the flu shot then (since it always gets me sick for a day) and just writing off that period before New Year’s. We never go out then anyway.

    When you roughed it out, how long did it take before you felt well? I’ve come off some doozy drugs like Cymbalta, but nothing has been as bad as this.

    Thanks for sympathizing.

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  • By Katie M. Golden Moderator

    Lynnv,
    You may want to think about cutting your 25mg in half to stretch them out longer. And the lower dose may make it easier for you than going directly down to 0. Just an idea.

    It was probably a month after I stopped Topamax completely before I felt better. I’ve also come off drugs similar to Cymbalta and that process is awful as well.

    Sorry, I wish I had a great trick to help you get through this. It’s tough!
    -Katie

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  • By Lynn Voedisch

    Hope you had a great holiday.

    I can’t cut my 25 mg. capsule in half because it’s a time-release capsule. I have one more to go. I got through Christmas in one piece.

    Wow, a month. I have these weird moments at night were I feel like my brain is rewiring. Hallucinogenic almost. I have to close my eye until it’s over. Hope that doesn’t last too long.

    Have a great New Year.

    Lynn

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  • By Lisa Robin Benson Moderator

    Hi Lynn,

    I’m glad to hear you made it through Christmas in one piece. Hoping your journey of coming off the topiramate goes well. Coming off medicine is never fun. It’s funny what you described with your brain rewiring moments–sounds like something that happened to me when I was tapering up on a different medication (nortriptyline). Just wanted to let you know you’re not alone in experience the weirdness that can come along with medication changes. That being said, if any effects are long-lasting, dangerous, or troublesome definitely tell your doctor and you can certainly always be more gentle with the process of tapering with your doctor’s supervision.

    Be well,
    Lisa

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  • By Lynn Voedisch

    Hello again. Well, it’s been two weeks since I got off of Trokendi, and I still feel like a wreck. The first week (the one between Christmas and New Year’s) was just awful and I was pretty much in bed the whole time. I ventured out a little, but not much.

    I went to the health food store to get some de-tox vitamins and herbs. I have this package called Whole Body Cleanse, and I thought it might help get out the remaining traces of topiramate. Instead, the darn stuff made me sicker. I have IBS (which was being controlled by a gluten-free diet), but the laxatives in the Whole Body Cleanse just gave me diarrhea and nausea. The booklet said to forgo the laxative if this happens. No problem there! I already decided to pitch them. But I’ll stay on the vitamins and herbs and see if it helps.

    Lisa, you said it was a month before you felt better. Here I am at two weeks and I’m still just a mess. Do you have any tips on how to power through this?

    Lynn

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  • By Lynn Voedisch

    Oops! I guess it was Katie who said it took her a month to get better. And she had no tricks or tips that would help. This is going to be murder…

    BTW, How do you get your picture in the little box above your screen name?

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  • By Katie M. Golden Moderator

    Lynnv,
    So sorry to hear that coming off of Topamax has been this hard. While you were tapering down, did your doctor give you another drug to replace it? My doc had me taper UP on Zonegran while trying to stop Topamax. Not sure if it would work for you, but maybe something you could ask your doc. Zonegran has a lot less side effects than Topamax. Yoga and meditation can help, but it will continue to suck for a little while.

    And to add your picture, go to the very top of any page that you have open. Look to the right of the banner that says “Migraine.com.” In small letters it should say “Welcome LynnV” and then there is a hyperlink you can click that says “Profile”. There you can add a picture. I hope that helps.

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  • By Lynn Voedisch

    Hi, Katie. I’m at week four now. Doing better but I had a weather headache (crazy barometer moving up and down) that resulted in a two-night headache and it ruined one day and part of today. I’m so exhausted from it.

    My doctor decided not to give me Zonegran or Lomotrigine because they both are seizure drugs (like Topamax) and likely to still cause kidney damage now that it’s obvious that I’m so vulnerable to it.

    He put me on Namenda, which was originally used for dementia (!!) but is now being used for pain diseases like fibromyalgia and migraines. It’s supposed to block the pain pathways. I have noticed that I have had fewer headaches and they’ve been less severe (except for the last one). I’m still only on half strength of Namenda though (10mg.). I keep asking when he’s going to take me up to 15mg. But you know how they want to get a response out of the least amount of medicine, so he’s going slowly.

    Funny you mention that about yoga. I don’t do yoga (has to do with my neck, long story), but I had been taking tai chi. I could do that at home as I don’t need a teacher anymore. I meditate every day, so that has not changed.

    I switched to a Liver Cleanse and am hoping it will get all the nasties out of my body.

    Lynn

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  • By Katie M. Golden Moderator

    LynnV,
    Thanks for the update. Besides your recent 2-day Migraine, it seems like maybe the worst is behind you? I’m sure you’re not feeling 100% yet, but it’s getting better?

    I’ve been on Namenda as well. It was weird to hear that it was an Alzheimer’s med. I had insurance issues with it. The science behind it is that Namenda works on the CGRP peptide that is believed to also cause Migraines. There’s a lot of research going on right now about its benefits for Migraines and it’s possible that a new class of drugs could come from this, which is very exciting. Here’s some more info about it:
    https://migraine.com/blog/what-is-calcitonin-gene-related-peptide-cgrp/

    I’ve never tried Tai Chi but can really see how it would give similar benefits as yoga and it’s a great substitute for you because of your neck issues.

    I hope that in a week or two you’ll really be feeling better. Keep us updated!
    -Katie

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  • By Lynn Voedisch

    I think I’m getting better. I still very fatigued and dragged out though. I started exercising again when I have no head pain, but only gently. The side effects of withdrawing from Trokendi has really aggravated my IBS, which I had gotten under control with a gluten-free diet. You don’t want the details, but it really messes you up.

    That’s really bad to hear that your insurance company wouldn’t cover Namenda. There was a drug called Zyprexa that my old migraine doctor (now retired) would give me. It got rid of periodic headaches like a charm and soon all the doctors in the clinic are using it. It was an off-label bi-polar drug. Finally, my old insurance company refused to pay for it, saying was a bi-polar drug. Seemed to happen to everyone, because the doctors stopped even getting samples. Too bad.

    That article link about Nameda was incredibly helpful and interesting. Thanks!

    I still haven’t tried doing my tai chi yet. Part of the problem is there’s not enough space in the house to do it right And I hate doing it at the gym because everyone gives me such strange looks!

    So, still tired and dragging. Hoping to get out of this.

    Lynn

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  • By Lynn Voedisch

    I had a really bad migraine last week that needed intervention from the clinic. (They mentioned the hospital again, but I refused.) Sure enough, it went away the day after I called them.

    I think I’m feeling like myself now. Thinking’s better and not dragging around. Started exercise, which is not a drag now.

    Wow, that toprimate withdrawal was a bear.

    Lynn

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  • By Katie M. Golden Moderator

    Lynn,
    So glad to hear things are getting better! I always know that when I feel like exercising, I must be better too. Tapering off Topamax is so hard and I commend you for sticking with it.
    -Katie

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  • By kimberlyflick

    Seeing as this thread is about Topiramate withdrawal, I wanted to add my current experience and see if it is in line with what I believe to be the symptoms of withdrawal.

    My neurologist is tapering me off of Topiramate and Citalopram to eventually have me on Venlafaxine 37.5 twice a day. After being on both previously mentioned meds for at least 9 years, they are no longer effective. I have gone up to 200mg of Topiramate and 40mg of Citalopram with no luck. My headaches are worse. My osmophobia is out-of-this-world. I can’t stand little things – hand sanitizer bothers me now. So, doc suggested we switch to an SNRI to hit two different receptors. Okay, I was pretty sure that was going to be his suggestion.

    I’m on the second week of tapering. Down to 20mg of Citalopram and 100mg of Topiramate. I’ve been nauseated all week and felt like a headache might be coming on. Yesterday it started. I took Tylenol 3 first because I hate abortives and sometimes I can stop the migraine with codeine. But it didn’t work so I used Migranal and went to bed. I wake up 2 hours later and it feels like nothing has changed so I use the Migranal again because I figure, ok, now it will work.

    Well, it didn’t. My last resort at 4:30 am was Fioricet which I don’t take unless I absolutely must. And this was a must. I took that and 1/4 a promethazine and knocked myself out for a good 5 hours.

    Currently, I’m not in as much pain but the pain has shifted from the right to the left and it still has the “ice-pick” feel to it. I feel like the Migranal didn’t work because this headache was linked to Topiramate withdrawal. Is that a possibility? I’ve always been worried about going off of this med because I know it can cause seizures if done too quickly but I’m not worried about that because I’m falling the regimen my doc prescribed and I do trust him.

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  • By vitamin_migraine

    Hi! I’m the original poster! To be honest, I have little memory left from that period. I don’t believe the Dopamax was effective — I believe it left me so tired and lethargic and out of it I couldn’t function or give two shits about migraines. The withdrawal was horrible. Probably lasted three months. And my left arm still constantly falls asleep. I think that is permanent at this point.

    Then I was back to my regular pattern of daily debilitating migraines, but I slowly started writing, reading, gaining the weight back, etc.. With my prednisone abortives, I made do.

    Four months ago my neurologist placed me on methazolamide (a glaucoma med). It took a month to have any effect and two months for full effect but I now have only one migraine a week, with known triggers, and auras *only* before a migraine, alerting me in time to take an abortive. I cannot express how amazing this is. Now I can tell if it’s lack of sleep, eating oranges, etc whereas before I had constant vertigo and visual auras. Now if I see lines or flashes of purple, it’s unusual. Unusual!! And the auras are far less intense, the migraines as well (a 6/10 v. periodic requests to have my eye surgically removed).

    So that’s just an update. Everybody responds to drugs differently, but to find something that’s effective and has basically no side effects (especially considered to Lamictal or Topiramate)… I know it’s an off-label use, but if you have multiple medication intolerances and highly complex migraines, it’s worth a talk with your neuro. Now migraines are just annoying, but not stroke or seizure like. I can socialize again and not be this weird medical anomaly in and out of hospitals, scaring my friends by fainting or going blind or slurring my words. It’s a game changer.

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  • By Lynn Voedisch

    I recently came off 200mg. Toprimate and I had a horrible time. The Ice pick headaches you describe are right on the money. I also had headaches switch sides. But they always responded to triptans. (Don’t know what Migranal is). I do have Narco when things get really bad and that did get rid of at least one. Fiorinal was a big no-no at my clinic. My bigger problem was constantly feeling like I had the flu, no energy, no appetite, just blah. Hard to work it got worse with each step down.
    As in Katie’s experience, it took a month before I was myself again.

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  • By kimberlyflick

    Day 4 of Ice Pick Headaches. I’m about to turn myself over to the nursing home, which doesn’t seem like a bad idea at times. My job requires I stand all day so yesterday was hell. I stayed all day though I was nauseated and crying. Today I’m home. I could’t take it. Called my neurologist and was told to go back up to the original 200mg Topirimate for now and continue the 75mg Venlafaxine.

    He gave me Axert in place of Imitrex due to the many drug sensitivities I have. Took it a few minutes ago and it seems to be working for now. We’ll see how long that lasts.

    Migranal is a DHE nasal spray. The DHE shots are what I have discovered work the best for me – kill the headache within 2 hours. But the shots aren’t available currently due to supply shortage.

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  • By Michelle Rudder

    I have been on many medications, for depression, for migraine and for allergies, all of which have nasty mithdrawal symptoms. I have found that a benzodiazapines like clorazepate or even diazapam addressed withdrawal symptoms for antidepressants and anti-convulsants (Topamax is an anticonvulsant). Talk to your doctor about this.

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  • By Lynn Voedisch

    Just a quick note here. Two months after going off topiramate I had a kidney blood panel and ultrasound, and my kidneys finally check out as normal again. This has been the scariest thing I’ve ever gone through with any drug and I just hope people pay attention to the significant risks that Topamax can pose. My memory is coming back and my hair loss stopped.

    It’s just a rotten shame that the Topamax worked so well when things were going well. I had a good two or three years with NO migraines at all.

    Now I’m on Namenda and it’s not helping much, but at least my organs are all healthy again!

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  • By vitamin_migraine

    Lynnv: you’re freaking me out because I’m vlynn usually on message boards. You’re like my parallel universe migraine doppelganger!!

    What really really truly brought me relief was methazolamide, a glaucoma med. But I had a severe case of complex migraine with the worst part being severe aura continua. But if it’s more the auras than the pain that bothers you, I’m actually down to 1 migraine a week or two, very simple, minimal aura, easily controlled with almotryptan. To me this is miraculous. I was a daily migraineur. Daily for years. Perhaps ask your doctor if he has heard of this treatment? The only side effect is really excessive peeing, but that’s it. Miracle! I say this and I have a migraine now… But I’m not needing to take prednisone or go to the ER. Miracle.

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  • By Lynn Voedisch

    Hi, vlynn,

    That’s funny about our screen names. I usually can’t get lynnv because it is already taken so often. Got lucky here.

    I don’t auras at all, so I doubt your off- label glaucoma med would work for me. After my Topamax/Trokendi debacle, I think I’m going to try some non-medical alternatives. hypnotherapy worked wonders for a while, but it wore off. I think I’m going to go at it again and listen nightly to audio affirmations. If I can make biofeedback work, it shouldn’t be that hard to get the subconscious to work on a deeper level.

    I’m pretty tired of being a lab rat for all these medicines they try on me. Some days I just end up in tears wishing I could be normal again as I was in my 20s (ages ago). But I soldier on.

    Best to you,
    Lynn

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  • By daffodil

    I withdrew from Topamax in December 2014. I was really unhappy to discontinue it because it literally saved me from the most horrendous hormonal migraines imaginable. I had to come off because I developed severe twitching in my eyelids after 5 years of use. I was on 100mg per day and tolerated it pretty well. I did have some eye issues (pain, redness), but they were tolerable. However, in early 2014 I developed a twitch in my left lower eyelid. This went on 24 hours a day every day! Because I had been on Topamax for so long, my doctor and I did not attribute this to Topamax. After about 6 months of this constant twitch, it started to occur in my right eye as well. I had also noticed that the twitching was at its worst about an hour after taking the tablet. I started to experiment with taking the entire dose in one hit. Prior to this I took it in two doses – morning and night. The twitching would start about 2 hours after I took the dose, but would eventually stop as the dose wore off. As soon as I took another tablet, the twitching would start over. We also experiments with lowering the dose to 50mg. This made no difference. As soon as the tablet was consumed, the twitching would start soon after. I also developed a tremor in my left hand which scared me half to death.

    This left me in a predicament because I was put on Topamax because all other prophylactic medications caused weight gain or drowsiness. My doctor told me about Relpax and said that he was getting good feedback. You take Relpax as soon as you feel the migraine coming on. Relpax worked amazingly well for me, but it does cause rebound migraines and my initial prescription of 4 per month had to be increased to 8 per month. Taking this much Relpax didn’t sit to well with me, so I started looking for alternatives.

    I have medical family as my two older brothers are doctors. One of them mentioned that a blood pressure drug called Candesartan was being used for migraine and the results were looking really good. I am currently taking 8mg of Candesartan per day without a single side effect. Apparently this does not have the weight gain effect of other prophylactic medications and so far, I would have to agree. It appears to be working as well as Topamax for me.

    In summary, there are other good drugs out there to try. If you develop a strange symptom, even years down the track, it can be attributable to the medication. For me, I no longer have twitching or tremor and my eyes no longer get red and sore.

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  • By dpasek

    In my experience, the anti-convulsants are just pure evil. Horrible side effects and absolutely no effectiveness in reducing the frequency of migraines. It has been several years now since I swore off this entire class of meds, but there are two in particular that are memorable. Topamax was the worst. I tried it for about 6 months, got gradually increasing paresthesia in my hands and gradually increasing cognitive impairment to the point where I became accident prone, almost severely injuring myself a couple of times. When that happened, I quickly ramped down, I think over two weeks, to quit the junk as soon as I could. Zonogran was another disaster, but it did not take as long for me to quit that. I was in a study on that one, and it started to cause extreme irritability after about 2 weeks of ramping up the dosage. The irritability came on rather suddenly, over only a couple of days, to where I felt like I wanted to jump out of my skin. I quit that stuff immediately in a single day and the symptoms receeded quickly. I called the doc and withdrew from the study.

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    • By Katie M. Golden Moderator

      @dpasek,
      Thanks for taking the time to explain your experience with Topamax. It helped me for years and then I moved to Zonegran and tapered off that completely. A lot of people swear by it and everyone’s reaction to it is different.

      Slowly tapering up or coming down is really important. Some people who have side effects like you described can tolerate it better if their dosage is reduced. I know it was really hard for me to come off of it as well. I’m glad you listened to your body and realize it just wasn’t for you.

      I think the article below is great about things to consider when trying a new med, whether it’s Topamax or something else. Again, thanks for your input!

      https://migraine.com/blog/weighing-the-risks/

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  • By Riotgrrl

    My neurologist had me drop from 200mg to 100mg topamax (or Dopamax, as I prefer to call it). The rebound migraines and all that “fun stuff” were bad enough. He just had me quit 8 days ago cold turkey the 100mg Dopamax. Just started Zonegran. My anxiety is flat-out panic attacks. Can’t focus, can’t do hardly anything. Is this withdrawal? How much longer will it go on?

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  • By Katie M. Golden Moderator

    Riotgrrl,
    This sounds like it could be related to the severe stoppage of Topamax. Most doctors wean you off it slowly such as taking you down 25mg at a time. It seems like you went off of it too fast.

    Zonegran is a good substitute for Topamax, and something that I did. Ask your doctor about increasing the Zonegran to avoid these panic attacks.

    I’m not a doctor so it could be something else. Talk to him about it.
    -Katie
    Migraine.com Moderator

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  • By mybookroom

    I just stopped taking Topiramate and my headaches are back but also my blood pressure has risen a LOT. Has this happened to anyone else? In only one week my blood pressure went from 120/80 to 145/90 which is a big change for me. I am worried and thinking of going back on Topamax.

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    • By fkristin

      Hi- I see it’s been a while since anyone has posted. I just started my second week into a 3 week taper of topamax. I am currently on 25 mg once a day. Week one, I began taking it every other day, week two every two days, week three every three days, and then stop completely. Week one went well I noticed no side effects from the withdrawal. Week two, this week… I have noticed an increase in my anxiety, weak feeling in my arms, and like mybookroom my blood pressure has increased significantly. Did anyone else experience the heighten anxiety? If so, for how long?

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  • By Nancy Harris Bonk Moderator

    Hi fkristin,

    Thank you for your question. I’m sorry to hear you are not feeling well while tapering off Topamax. I don’t remember much about tapering off it I’m sorry to say, that was a number of years ago. Hopefully others will be along shortly to share their experience with you.

    Now having said that, I do know it’s not uncommon to have a rough time when discontinuing medications. If this continues, please get in touch with your doctor and/or pharmacist for help easing these symptoms.

    Will you keep us posted on how you are doing?
    Nancy

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  • By StacyLea

    I am currently trying to wean off Topiramate. I was on the medication due to severe migraines than would last for days and would affect my speech and fine motor skills. I had all the tests done and ruled out any other illness. The meds are causing confusion and memory loss and my cognitive abilities have slowed dramatically and I stay tired! I went from 100 mg down to 25 mg currently and I feel awful. I ache terrible and over Christmas break when I am off work, I plan on going completely off. Something has got to give because I cannot work and keep taking this med.

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  • By Nancy Harris Bonk Moderator

    Hi StacyLea,

    I’m sorry you are having a difficult time right now, that is frustrating. Are you tapering off Topamax slowly? Sometimes when we slowly taper off it, some of the side effects may lessen. Suddenly stopping Topamax can create new problems and it’s suggested to taper off it by 25mg per week to avoid other problems, like seizures.

    I hope things improve.

    Wishing you a safe and happy holiday season!
    Nancy

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