Beta-Blockers medications for the treatment of migraine headaches : an introduction
Beta-blockers, commonly used for treating high blood pressure and other heart issues, are also prescribed to prevent migraines. Beta-blockers are also sometimes called beta-adrenergic blocking agents.
Studies show that beta-blockers reduced migraine frequency in 50% of studied patients.
How beta blockers work
Beta-blockers work to relax and open up blood flow in blood vessels. Changes in blood vessels in the brain are thought to cause migraines, however it is unclear how beta-blockers prevent migraine symptoms. Beta-blockers also block the effect of adrenaline, reduce blood pressure and slows the heart beat.
Side effects of beta blockers
- Fatigue
- Nausea
- Reduced ability to exercise
- Insomnia, sleep problems, nightmares and vivid dreams
- Memory problems
- Depression
- Weight Gain
- Exacerbation of asthma
Who should not take beta blockers
People with asthma, emphysema, moderate to severe chronic obstructive pulmonary disease (COPD) and unstable heart failure should not take beta blockers. Also those with high blood pressure or the circulatory problem, peripheral artery disease are advised against taking beta blockers.
Different beta-blockers for preventing migraines
- Propranolol – Inderal LA for migraines

Related articles & posts
Written by: Otesa Miles / Reviewed by: John-Claude Krusz, PhD, MD | Last review date: November 2010. Click the References Link below for a complete list of references.
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There are over 1,000 articles and stories on Migraine.com - but we have the tools you need to find the information most relevant to you.http://www.medscape.com/viewarticle/494023
Prophylactic treatment of migraine with angiotensin II receptor blocker; JAMA; Tronvik 2003
http://www.webmd.com/migraines-headaches/beta-blockers-for-migraine-headaches
Best Buy Drugs, Consumer Reports, Beta-Blockers 2009
http://www.aafp.org/afp/2006/0101/p72.html
http://www.mayoclinic.com/health/beta-blockers/HI00059

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