hi there. That is a great question. I was on Topamax for about 15 years. It was very helpful, but, I started having some side effects. My neurologist recommended Depakote. We tried it only for a short time, about 2 weeks. I decided to stop because I was not feeling too well on it. I had stomach pain, sleepiness and nausea. I wanted to share this with you: https://migraine.com/migraine-treatment/depakote-and-depakote-er. That discusses the medication and potential side effects. Here are 2 articles about the writers experience with it: https://migraine.com/living-migraine/depakote-infusion. https://migraine.com/living-migraine/stopping-attack-that-wont-end.
I hope that if you try it, it will make a positive difference for you. (Tonya, team member).