CGRP Worked-- For A While

I was one of the first in my doctor's practice to start Aimovig. I knew that the CGRPs were arriving, and I was excited to have a new treatment option. At the time, I was having 3-4 severe migraines per week, and my quality of life was poor. I was managing to work, but I could not do much else. Most of my weekends were spent on the couch.

I felt a difference as soon as I started Aimovig. I went days, even weeks without a migraine, and when I did get them, they were much less severe. I started doing things I hadn't done in years--walking to work, taking piano lessons, making bread--it was like a new life!

Then I hit the end of the first year. 2 months ago, I took my Aimovig injection, and I had a 5-day migraine. I thought it was because it was the first time I used the 140mg syringe (I had been using 2 70mg syringes.) I asked my neurologist to prescribe the 70mg syringe, and the same thing happened two more times.

I spent the last four days with a severe migraine, with more nausea than I usually get. I am also having more problems with severe constipation.

I have decided that I will take a break from Aimovig. But I am unsure what to do next. Should I try a different CGRP? I really did not get any relief from other preventatives. Has anyone had any experience switching CGRP drugs?

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