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Postdrome is a Downer

You know that scene in the movie – the heroine has finally limped her way to the front door. No sign of the monster chasing her. This is it! She’s going to get away! And, just as she gets halfway out the door, the monster appears from the shadows to pull her back into the house. That monster is for me is depression and the door is the end of the active phase of my migraine.

Migraine causes fluctuations in serotonin, a neurotransmitter that correlates with depression. For me, the aftermath of the migraine can be worse than the crushing fatigue, nerve pain, sensory sensitivity and nausea. Maybe it’s because I think I’ve made it out like that leading lady in a horror film. I think I can finally recover and go back to my life until that hope is snatched away.

Depression tells me I’m fat; I’m ugly; I’m not going anywhere with my life; I’m going to be alone forever; I’m weird; and today it told me that I have terrible taste in clothes (rude!). The more frequent the migraine attacks, the more the mood fluctuations. And, it’s hard enough to stay positive with migraines as it is.

Aimovig is helping the frequency and duration of my migraines, but there’s no cure yet. I just have to remind myself that depression is a liar and that just because I feel awful about everything, doesn’t mean everything is awful. And, pizza. Pizza always helps.

Do you have depression with your postdrome?

This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.


  • AZReynolds
    5 months ago

    For me, my migraine is often followed by fibromyalgia flare ups. I am not sure if it is the meds or if it is part of depression. All I know is that it hurts and I only want to sleep. I avoid taking my migraine meds because they make me feel so bad, but currently Relpax is the only triptan I can take. So, knowing this is a possibility, I try to just float through it, accepting the inevitable but knowing it will pass eventually. I try to use it as my time to reflect on my life, past and future, and time to practice mindful meditation.

  • Nikita212
    6 months ago

    I get depressed and exhausted, along with feeling space after a migraine. The predominant feeling is that this disease will never end. I go down the rabbit hole of never having my life back, always tip-toeing around triggers and not having enough energy to go out for long–especially at night.

    A few days later, even though I have the same considerations, I’m busy living and don’t feel so bad about it.

    It’s an ongoing cycle. I find staying in the present as much as possible and allowing myself some accommodations (like adding in an extra recovery day or two when traveling) helps me manage a challenging disease.

  • Luna
    6 months ago

    I don’t know where postdroom ends and prodrome begings. It all runs together and depression to varying degrees runs through all of it.

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