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CGRPs (calcitonin-gene-related peptide)

Aimovig – Unsuccessful for me

  • By Texs4

    I’m two weeks past my third 140 mg dose and no changes to my chronic migraines symptoms, which are daily. I recognize the clinic research identified that improvements may not be experienced until after the fourth dose, but my side effects are escalating with each dose. At this point, I’ve been taken off Aimovig. It’s another failed treatment to be added to the laundry list. I’m so frustrated and feel my physicians are throwing up their hands because I’m so difficult to treat… I’ve such a low tolerance to medication and my health continues to decline. My career has stopped and my attempts at diversion therapy are minimally effective. I’ve been struggling for two years and am mentally and physically exhausted.

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  • By Nancy Harris Bonk Moderator

    Hi Texs4,

    Thank you for sharing your difficult journey with us. I understand how disheartening it is when yet another migraine medication fails. Please don’t lose hope! There are two other CGRP medications out that may be better suited for you. Each of these CGRP medications work in subtly different ways.

    May I ask if you’ve seen a true migraine expert – one who is board certified in headache medicine, which is different than being certified in neurology?

    Let me know how you’re doing,
    Nancy

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    • By Texs4

      Hi Nancy – Yes, I am currently seeing a board certified nationally recognized migraine specialist. Its been a painful learning curve and after three neurologist “headache specialist”, I feel that I’m finally on a good path. That said, I struggle daily to stay positive and try to keep my career. I appreciate that my case has many complications, but I’ve found that the medication side effects are frequently worse than dealing with the migraines. Have you ever been in that situation? I’ve become cynical and I’m not eager for Botox—the current proposed treatment.

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    • By Nancy Harris Bonk Moderator

      Hi Texs4,

      I truly get it. I hate that it takes so long to be correctly diagnosed and then longer to find a treatment plan that works. Another problem many of us run into is an established plan will cease to be effective after a while, and we’re back to square one.
      I put off Botox for many years, I was nervous about possible adverse effects. I’m now going on 2 years with it and it has made a difference in my attack frequency and severity. My abortives seem to work better as well. It’s not a “cure” but another tool to help prevent migraine attacks.

      Here’s to a pain free day!
      Nancy

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