Expert Answer: Blood Platelet Count & Migraines

Question: What does blood platelet count have to do with Migraines?

Platelets are indeed involved in the development of migraines. They tend to become sticky and release serotonin which is intimately involved in the migraine process. Aspirin, among other effects, prevents platelets from becoming sticky and that is how, at least in part, it is thought to treat and prevent migraine headaches. The actual number of platelets, or platelet count is also important to know because people who have too many platelets (a condition called thrombocytosis) are more likely to develop headaches. Actually, headache is one of the most common neurological symptoms of thrombocytosis. Effective treatment to reduce the excessive number of platelets will usually improve headaches as well.

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Comments

View Comments (15)
  • Molly Sweeny
    7 years ago

    Has anyone tried daily aspirin as a preventative? or nattokinase? or white willow bark? love to know!

  • Bonna Mullaly
    8 years ago

    Hmmmm, now that makes me want to check my lab results from last summer’s physical. I remember thinking wow I almost have too many, but I honestly don’t remember if it was just a high red blood cell count or the platelets or are they one and the same? So what is the treatment if you do have that?

  • Bonna Mullaly
    8 years ago

    LOL so many of them do. That’s why I’m so picky about who I go to and tend to stay away as much as possible!! What’s creepier though is a person who has a snake oil cure for them……..

  • Lisa Brechler Houghtaling
    8 years ago

    That migraine expert looks very creepy ….

  • Andrea Turner
    8 years ago

    I am wondering if dehydration to some extent would play a roll in this as well. After watching another migraine sufferer I noticed she got them more often when dehydrated to some extent but not overly so.

  • Julie Graber-Doyle
    8 years ago

    Thank You for your help.

  • Nancy Orlando-Bell
    8 years ago

    Now why didn’t I think of that! Huh!

  • Migraine.com
    8 years ago

    Dr. Mauskop answers your questions regarding the relationship between blood platelet count and migraines.

  • Tina Maroon
    8 years ago

    what about taking a lot of toradol or motrin

  • Fatima Diane-Marie Samson
    8 years ago

    I take aspirin and my headaches have been somewhat better. But I have too many platelets too. What to do?

  • Katie MacDonald
    8 years ago

    Interesting. One of the preventative medications I took for migraines resulted in my platelet count being too low. I never knew there was a relationship between platelets and migraines though! Thanks.

  • Wendy Andras Strother
    8 years ago

    Makes sense to me.

  • Suzi Dean Paullin
    8 years ago

    Interesting……

  • lizzie
    8 years ago

    I’ve had migraines for 40 years. Several years ago I was hospitalized due to extreme dizziness and suspicion of stroke, which was ruled out. During testing it was discovered that I had plaque in carotid artery and also a hole in my heart. Cardiologist prescribed Plavix and told me to continue taking it forever. I also take two BP meds. I still get frequent migraines, but they haven’t been as severe since menopause and seem to be more weather and food related.

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