Hi Tamara and Nancy, I have tried many regimens, but not Baclofen to my remembrance. I'm enjoying migraine free days 10 to 15 days a month now using Fioricet as my rescue med; Ketorolac for headaches that last four days or more (have to be very careful with this one. Only use very short time periods in extreme situations); Propanerol 3x a day; magnesium daily; at night Tizandine, Diazapam, Amitriptyline (soon to be changed to Nortriptyline); and Botox injections every 12 weeks. I've used Cambia, which was effective rescue med, but that was taken away due to strokes, also have tried many other meds/regimens/rescues over the years. My Headache Specialist is excellent and he suggests changes depending on new info and how I am responding to treatment. I found it interesting, Nancy, that you use Tizandine as a rescue med. I often wake with migraine now, so it was added to my nightly regimen. Nothing has prevented me waking up with migraine, so I'm going to discuss with my specialist trying it instead as rescue. Will give me another option since the Fioricet is so limited to avoid rebounds. Tamara, I wish you the best in getting a knowledgeable headache specialist, and in finding a protocol that is more effective.