I've had hemipeligic migraines since age 12 .I'm 59 yrs old currently. I have other "migraines" every 10 days I get a three day migraine. When the weather changes, which in New England, is every 5 minutes. I have taken topamax which apparently caused neuropathy. I have taken propanerol which caused excessive sweating and weight gain. Verapamil made me cry( I never cry). I've done trigger point injections, Botox and multiple rounds of physical therapy. I have interstitial cystitis which flares whenever I take anything like maxalt or omitted. I'd rather the migraine because the IC is far worse. My dr has no suggestions. I've asked for another round of Botox because it did help for awhile.? Does anyone have any suggestions for preventive medication? The only thing I take now is fiorinol! I'm at a loss!