, my husband takes magnesium glycinate every day at 400mg as this form of magnesium helps calm his nervous system and eases migraine pain. He also takes magnesium L-threonate to help with brain fog at 200mg daily. For him, this counteracts the majority of constipation he gets from taking CGRP antagonists. As for me, I have to take magnesium citrate as this has a more laxative type effect at 400mg daily. As with so many medications and supplements, our bodies metabolize and react to them differently. I am attaching a link to a study that explains the effects of CGRP in our gut that you might find interesting.
https://www.frontiersin.org/articles/10.3389/fphys.2021.820006/full
The use of magnesium varies based on the elemental form of each type. Some can cross the blood-brain barrier, while others do not. Different forms have different bioavailability in our bodies. Label reading when choosing supplements is also important, as the front label may state a certain milligram, but the supplement facts on the back will indicate the exact specifications and the number of pills needed to get the stated milligrams. A 400mg dose may be included in one pill vs four based on the manufacturer and if fillers or other ingredients are added to the pills. I know this is a lot of information, and you may not find all of it useful but there it is, lol! Have a great day, and thanks for being part of our community. Warmly, Cheryl migraine.com team