Excruciating migraines started in my teens. Doctors were no help. It's taken years of record-keeping and experimenting to find my own answers - for almost no cost. They might work for you too - IF you have the same genetic makeup. I want to share my observations here, for others ready to take action. It's your choice. Either take time and personal responsibility, like a precise log, and gene test, or just keep waiting for someone else to find some magic bullet.
You see people here asking "What worked for you?" Without also asking "What symptoms or genes might we have in common?" There are at least a dozen different migraines linked to specific genetic mutations, some affecting K, Ca, Na concentrations in the brain. One clinical trial on a drug that had worked for me was called inconclusive because too few were cured - ignoring our positive results, or any thought to our "exceptional response." NIH has just started an "exceptional responders initiative" to identify WHO responds to WHICH treatment (for cancer, bit it's a good example for migraine).
MY analysis of MY case and MY cure (vastly simplified).
I soon discovered that my best pain therapy was just a few hours of sleep. Then known lifestyle changes stopped pain from even starting. Eventually I also found I have a 1-in-20 genetic mutation which creates too many platelets, which temporarily clogs blood vessels, which precipitates aura, which led to migraine. This clogging also contributed to hearing loss/tinnitus, TIA lesions, and retinal clouding. Some day genes won't be destiny, with the invention of gene-fixer CRISPR. But instead of waiting, I simply counteracted the platelet problem with clopidogrel. This finally stopped most auras, which could have been the real problem from day one. Daily aspirin might have been an even cheaper fix - for MY case.
Want to re-analyze your own?