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New Treatment Experiences Part One: The Success Stories

The new CGRP treatments are certainly a hot topic right now. On’s Facebook page, we reposted Holly Baddour’s piece, “CGRPs and Migraine: Navigating Wellness for the First Time in Years.” Her article sparked so many reactions. In a separate Facebook post, we also asked the community if you had talked to your doctor about trying new migraine treatments.

Some of you spoke out about how these new medicines are changing your life. Others of you agreed with Holly’s concerns about cost and insurance. Unfortunately, some have not found any relief from the new treatments. In this three-part series, we will be sharing comments from these community posts that included success stories, scenarios where trying new treatments led to no happy ending, and cost and insurance concerns that may stop you from trying new migraine treatments.

“CGRP treatment has been a game-changer for me. I am thankful.”

There is a reason so many people are talking about CGRP treatment. People in the migraine community have had success with trying one of the three CGRP treatments, Aimovig, Ajovy, or Emgality. They are finding a drastic decrease in the number of monthly migraines and have said it feels like they have a new life now that they are on the new CGRP treatments.

“I started on CGRP (brand name) in July and after three doses, it seems as though we hit the jackpot! In two weeks I have had only one migraine! That is a miracle for me! Haven’t had that in 20 years. I have everything crossed that it keeps working! Don’t give up folks and good luck!”

“My entire life has changed for the better. I am more respected at work, am able to have a healthy relationship with my family and have a bf for the first time in five years. I am so thankful for CGRPs (brand name)!”


“CGRP treatment has changed my life completely!”

CGRPs certainly has its fans in the community. Many of you have made the switch, and couldn’t be happier. Many mentioned a reduction in migraines—sometimes a drop from as many as four a week to one a month. No wonder members who have found relief from this treatment have become so loyal.

“CGRPs (brand name) has been life-changing for me. I started in January on the 70mg dose, and noticed a great improvement, but still some migraines. In April I was bumped up to 140mg, and I only had one migraine since then. Before starting, I averaged 6 or 7 a month. It is truly incredible for me, and I am so thankful I found a great neurologist and this treatment!”

“I’ve been using CGRPs (brand name) for about eight months this and love it. I thought that I didn’t really let my headaches affect my life but when I saw the difference in how I felt and what my life was like with reduced headache days, I was shocked at how much they ruled my life.”

“I have been taking CGRPs (brand name) for a year. I have noticed a great deal of relief.”

“I am about to take my third month’s injection of CGRPs (brand name). It has changed my life completely! Frequency and intensity of migraines have greatly diminished. Even my chronic daily headaches have improved. Tension headaches are still an issue at times, but I’m shocked at how well I’ve felt the last two months!”

“I started out with 70mg but am now taking 140mg.”

Also worth noting is that many of you who tried CGRPs have had to increase the dose. Because this is a newer medicine, less is known about how effective it is with patients—and how it works long term, which is something to consider.

“I have been on CGRPs (brand name) since Oct 2018. I started out with 70mg but now taking 140mg. It has been working but lately, I think my body has become gotten used to it. I’m wondering if I should talk to my doc about either switching from one CGRP (brand name) or another CGRP (brand name).”

“I was on the CGRPs (brand name) 70 mg dose for a year and just increased to the 140 mg dose. I also resumed my Botox treatment. Between those two, my migraine days are down to 20 per month. Still more than I would like, but an improvement.”


Hear more from the community

For more comments from the community, check out the original Facebook posts here and here.

Please stay tuned over the next few weeks for part 2 and part 3 of this New Treatment Experiences series and feel free to share your own story!

This article represents the opinions, thoughts, and experiences of the author; none of this content has been paid for by any advertiser. The team does not recommend or endorse any products or treatments discussed herein. Learn more about how we maintain editorial integrity here.


  • DizzyLizzy7
    3 months ago

    I tried one shot of Ajovy. had sever allergic reaction so stopped using it.

    Now Aimovig is suggested for me. Has anyone had an allergic reaction to Ajovy, but tolerated Aimovig?

  • GardensatNight
    3 months ago

    I am definitely a treatment success story. I have been on botox (plus other preventatives) since 2016. Once Aimovig was added to my cocktail of meds, my migraines went from chronic and intractable to a background headache I can manage most days. I still can’t be exposed to light or loud sounds, but to go from intractable migraines that lasted months at a time and left me curled in bed unable to function to being able to go about my day so long as I am in my house away from bright light… has been a miracle. When I get bad attacks now, they last a few days or a week. It’s no longer the 2-4 month nightmare with only a few days break in between it was before.

    It’s the combination of Aimovig/Botox together that has worked, and now we’re just struggling with insurance as they’ve refused to keep covering Botox as long as I’m taking Aimovig (even though it’s covered by the bridge program and we are not asking them to cover it after the bridge program ends.) To go back to being non-functional and spending my days curled in a ball in terrible pain, or hooked to an IV at the infusion center… I don’t want to imagine, and I’m trying to enjoy every wonderful day I’m having right now on these two meds.

  • Luv2TeachMath
    3 months ago

    I read your post and felt like it was something I had written! Being totally disabled with chronic and complex migraines, I never WANTED anyone to suffer through what I do on a daily basis, but to read your story lets me know that I am not completely alone on this end of the spectrum.

    Like you, I was doing great with the Aimovig and Botox. I was on Aimovig for over a year. Last January, BCBS tried to stop my Botox. I learned that the Dept of Insurance in the state I live has some sort of “Smart” program that will help you fight the insurance companies if you’re denied. If your state has something like that, then it may be an option for help. (They were actually filing the appeal for me!)

    Like you, the combination of Aimovig and Botox lowered my daily pain level by at least 2-4 points, and that’s something to celebrate! Unfortunately, 3 weeks ago, BCBS decided to deny Aimovig (because it was obviously working!). They stated that I needed to try one of the other 2 CGRP’s before they would allow me to get Aimovig again. (Like… “Let’s fix what’s NOT broken!”)

    I’m sorry that you struggle through so much on a daily basis, but thank you so much for posting!

  • Peggy Artman moderator
    3 months ago

    Thanks for sharing your story! I am so excited for anyone that finds a treatment strategy that really makes a difference in their lives. Insurance can be frustrating to work with, but hopefully people can stay on their treatment regimens without so much hassle. I do know that Botox has a good savings program.
    ~ Peggy ( team)

  • GardensatNight
    3 months ago

    Botox savings program only works through commercial insurance. I am being refused coverage on the basis that I am taking Aimovig (through the bridge program) and therefore do not qualify.

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