I think the fatigue many of us experience with migraine disease can manifest itself in all types of bodily systems. I wouldn't think it's a stretch to say you experience it in your eyes at all. My husband suffers from photophobia and that alone puts stress and fatigue on his eyes. He goes to the eye doctor regularly and his eyes are healthy, but he just has to deal with those aspects of the disease. Warmly, Cheryl migraine.com team