I've had migraines since I was 11 years old. I've tried just about every preventative med, acupuncture, massage, biofeedback, mouth guards, special diets, etc with no significant lasting results. For most of my adult life, I've had 4-6 migraines per month. Back in February, I just happened to try an all natural energy tea that I got at a sandwich shop, and it seemed like I was getting fewer migraines when I had the drink. So, I decided to test the theory by having one drink each morning with a breakfast sandwich. In the past 4 months, drinking one drink every morning, I've only had one migraine and that was on a day that I was extremely dehydrated. So, that's like a 90+% reduction in migraines for me so far. Looking at the ingredients of the energy tea, the only one I really haven't had before on a regular basis is D-Ribose. Research shows that D-Ribose impacts the energy production in mitochondria and it has been shown in studies to have a significant reduction of symptoms in people with Chronic Fatigue Syndrome and Fibromyalgia - but I haven't seen anything about its impact on migraines. I bought D-Ribose powder to try by itself - and found that it makes me really groggy if I don't take it with carbs - which is probably why the drink works so well. I've never had any unusual energy problem, except right before I get a migraine. And I've never had all over body pain - just migraines. So, I don't have any Chronic Fatigue or Fibro symptoms - yet, it appears that the D-Ribose has eliminated the large majority of my migraines. I'm wondering if anyone else has tried D-Ribose or found any info about why it could likely be eliminating my migraines. I know people get migraines for different reasons, but I would venture to say there have to be others like me.