Hi - I'm so sorry to hear that you haven't found any of the available medications helpful. Please know that you're not alone in this! Have you done any exploration on potential alternative and complimentary approaches to treating your migraines, such as acupuncture, chiropractic care, etc. I know that it can sometimes be annoying to be asked this question over and over, but I just want to make sure that if you haven't, we have lots of helpful info about it. Just let us know how we can help 😀. We're here for you! - Cody (Team Member)