Even though I am on a significant daily dose of Topiramate that generally is a very effective preventative, and I get Botox every 3 months, plus I take Maxalt (generic) no more than 3 days a week, an analgesic no more than 2 times a week, (because I get rebound headaches if I take anything more than that, & I don't take anything stronger than XTRA Tylanol for the same reason except once every 2 months or so), I still get these MONSTER MIGRAINES that last for 10 days. Now, I'm a chronic daily migraineur, and have been one for about 4 years. I've had migraines for 55 years. Never every day, as I do now, but much of my life has spent fighting migraine disease. The treatment I'm on now keeps me out of bed most of the time - except when these 10 day attacks hit. I just want to die, the pain is so unrelenting. I can take Maxalt during some of these 10 days, but these 10 day attacks are so severe, it doesn't work as well as it usually does at other times. Anyone else experience these?