Has anyone been on mexilitene as a preventive? Have you experienced side effects with it? I’ve been on it about 6-7 days. I started with one capsule a day then increased to two capsules about 2 days ago and today woke with fatigue and muscle weka was in my thighs along with some tingling in the thighs. I experienced this inpatient last month while on IV lidocaine. By the second day I had thigh weakness and fatigue and by the bird day could not walk. My legs would not supper me. I am Afraid the same thing is happening with mexilitene. My understanding is that it is a pill for of lidocaine. I am curious to know if others experience these symtpoms with mexilitene. I put a call into the headache center to discuss with them. I was rally hoping it would help as a preventive. Mel