Has anyone been prescribed prednisone for a long term migraine? I started to get migraines with aura for the first time almost 2 years ago when I was pregnant with my first child and since that time they have never stopped. I get migraines every week. I've tried many natural remedies as well as drugs. Currently I'm on Topamax but my migraines have become even worse over the past two months and its to the point where I'm no longer able to care for my son and my light sensitivity is so extreme I can't leave my house. My neuro has increased my Topamax, prescribed Maxeran for my nausea, suggested I retry my maxalt and frova (which previously had no affect), he's prescribed DHE spray and 5 days of prednisone. Anyone used a similar treatment plan? Success with prednisone?