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Seroquel...possible preventative?

Has anyone here had any kind of experience with the med Seroquel? I was put on Topamax again (long story in the Topamax thread), and it actually is working very well this time. 😀
I am wondering though if it might be attributed to being combined with my other meds. I started taking Seroquel for insomnia right about the time the Topamax started working well. It occurs to me that although I am taking Seroquel for insomnia, it is actually a bi-polar medication. Another well known migraine preventative, Depakote, is also a bi-polar medication. Since most of the off label meds are in groups such as seizure meds and beta-blockers, it makes since that other bi-polar meds might also work. So, has anyone else out there had a good unexpected experience with Seroquel? Or even any other bi-polar medication that is not currently thought of as a typical migraine med?

PS: I also take 2x 750 mg Robaxin every night to prevent occipital migraines

  1. Hi Teresa,

    Thank you for your question and I'm so sorry for the delayed response. I don't have any experience with Seroquel, but know others who use it with success. Hopefully others will be in shortly to share their experiences with you. Let's see what information I can give you to help.

    The medications used for migraine prevention were developed for other conditions and it was just a by product that they worked in reducing migraine frequency and severity and are used 'off label.' Divalproex, onabotulinum Toxin Type A, propranolol, timolol, topiramate, are the only medications currently FDA approved for migraine prevention, however they were not developed for migraine.

    Most of us are in fact on a combination of medications to help prevent migraine. If you put 10 of us in a room, you probably won't find two with the same combination. There are over 100 medications that can be used for migraine prevention I'll share that with you here;

    I hope that helps

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