Topamax can have some pretty problematic side effects that's for sure. I know the general recommendation for trying a new drug is two months, but that may vary depending on what you are experiencing and how you and your doctor want to proceed with the treatment. If the side effects are having a negative impact on your daily life and not improving your condition it may be time to ween off the medication per your doctor's advice. My husband had to stop taking Topamax after 6 months due to the severity of the side effects. I would take some time and speak with your doctor regarding what you are experiencing. Warmly, Cheryl migraine.com team