The subject says it all. Sorry for the length but I'm totally excited about this.
I've been trying to get my doctor to authorize a scrip for an oxygen bottle but he won't do it. I read long ago that sometimes pure O2 will fix a migraine at the beginning, midstream or at the end but I've been unable to test out the suggestion.
Well, I didn't realize that there's a ready source of O2 that doesn't require a scrip. I'm a grounded pilot (I didn't lie on my medical and they grounded me because of Imitrex) and there's a place here in Ohio that sells O2 for pilots and other "pilot supplies" so I bought a couple of small bottles on the cheap. I won't advertise for them so if you're interested you can google the keywords. Amazingingly, since I received the bottles my migraines have seemed to abated - it's been a week.
Second thing is I was talking to a buddy at work about migraines and he told me his wife has been taking L-Methyl Folate - this is a bioactive form of folic acid that is able to cross the blood brain barrier. They are in possession of one of those rare things - a doctor that knows their crap - a real-world unicorn - and he put her on supplement form.
There is also a prescription version called Deplin which is the same thing only much higher potency - it sometimes works wonders on folks with migraine and concurrent depression. He said his wife is taking the non-prescription OTC version (5000mcg x 3) verses Deplin (1 x 15000mcg). He said his wife has completely turned around - rarely has to take an imitrex and has tons of energy and positive attitude.
The research I've done on it suggests that people who have a genetic issue resulting in the inability to process folate (there's a really long name for it) are chronically low in serotonin. L-Methyl Folate seems to boost the pool in the brain and when used concurrently with SSRI's can make all the difference in the world in a very short period of time (that's for those with depression).
Imitrex appears to be some sort of serotonin agonist so L-Methyl Folate may actually work for migraine by replicating some of the effects on seritonin.
I'm going to order a bottle from my favorite massive on-line supplement provider and try it out. I'll report back my findings while huffing my oxygen bottles.