March 17, 2019
I've been on Emgality for 5 months and have gained 14 pounds. Prior to that I had (healthily) lost 20lbs. I have had no other med changes, diet changes, activity level changes. Is anyone else on a CGRP Receptor having this problem? Thanks in advance. DANA
Nancy Harris Bonk Moderator
March 21, 2019
Great question!! Yes, I'm sorry to report I've heard that these CGRP medications can increase our chances of weight gain from a number of people. 🙁
Holly Harding Moderator
June 25, 2021
July 21, 2021
March 22, 2019
Yes I’ve gained 8 pounds and I never gain weight unless it’s from medication.
March 25, 2019
OMG, I wish I had seen this post sooner!
I recently started Emgality - I'm on my 2nd month - and my weight has ballooned.
I gained 7-10 pounds seemingly out of nowhere and I've been at my wits' end trying to figure out where it came from.
It makes too much sense that it came from Emgality so I guess that's the end of it for me.
Diabetes and hormonal issues run in my family and so one of my criteria of any medication I take is that it needs to be weight neutral.
Two months and almost 10 pounds along with a sluggish GI is too much.
Tom Picerno Moderator
March 25, 2019
With the relative newness of the CGRP drugs people are starting to report all kinds of different side effects such as weight gain, injection site pain, etc. Thanks for giving us your observations. I'm on Ajovy and am in month four with no major side effects to report other than minor itching and mild constipation. Please keep us updated on your issues as your input is valuable to those of us who are on CGRP injections.
May 8, 2019
For those who find the injections very helpful but the weight gain around the waist area very troubling (and probably unhealthy), are they looking at anything that might counteract this side effect ?
June 20, 2019
As far as them looking for something to counteract the weight gain.... I haven't heard of one doctor believing that the weight gain is a true side effect of the Emgality. My thought is that if it is really working for someone, they should stick it out....if you feel better, you may be able to start becoming active again, working out....Jeez even just getting out of the house and that may combat the weight gain.