I am allergic (not just sensitive or intolerant) to almost every painkiller (paracetamol, codeine, aspirin and can take only limited opiates) and antibiotic. We've called in the ambulance a few times, and I carry an epipen.
We have to work with preventives for my migraine care, and environmental controls. It's not easy, because my issues don't show up in IgE testing. But I get all the classic signs - even in blind tests where an incorrect medicine is accidentally administered. It's not fun or pretty!
Kim, I'd suggest thar if you haven't, you should also check into the food chemicals area. Your issues may be exacerbated by preservatives, binders and dyes used in the processing and manufacturing of the medicines, as well as the substances from which they are derived. Since I've been back on the strictest low chemicals nutritional plan (4weeks), I've lost a shoe size, 2dress sizes in swelling, and gone down to 3 or 4 mild migraines a week. They were almost daily and left me barely functional.
(Friendly Foods is the plan I'm following, from the chemical sensitivity unit at the Royal Prince Alfred Hospital. It's also online)