Hey Codybone,
I've found for me a 100mg sumatriptan (the weaker 25mg does nothing for me however) and an ice pack works well, along with trying to find a cool, dark, quiet place to spend some time. At work they just about always have the a/c blasting, but dark and quiet is hard to come by. I do feel very drained as a side effect of the sumatriptan, but I'd much rather feel drained than get a killer migraine headache.
As Joanna said, there's no one size fits all answer. Best of luck to you in finding an effective treatment!