I currently use Midrin for my headaches. This helps my migraines significantly. This medicine was previously discontinued. My Dr. gave me a prescription for a compounding pharmacy. So being unavailable is not an excuse for using this drug. It has recently come back on the market through Macoven Pharmaceuticals. Midrin was discontinued because it was developed before the FDA became involved with product approval. That is the only reason. It was not because the ingredients were dangerous.