Hi! Found your board in google, please, let me know if you think there is better forum for this discussion, but I did not find any. All medical boards are closed or without members anymore. I am trying to investigate my migraine and other problems and link them together.
About me: 35 years old male, 180 cm, 85 kg. Migraine started when I was 18 years old. Its migraine with aura, always with prodrome, which can start even week before the migraine. I am pretty sure that my migraine is related to genetics - my mom also has migraine. My medicine is Ibuprofen which helps me good with blocking headaches, recently I' ve found that Magnesium supplements are also good and now I have migraine less often.
I also have some other issues, one of them is herpes simplex. I had a lot of outbreaks in the past until I found that I have serious D vitamin deficiency, then I started to use D3 and reached it's level in blood to 70 ng/ml and now I have herpes outbreaks very rare, but still have. But I know some people which never had herpes, however was in a contact with infected people for many times. I see, that in my family herpes is a common issue, so I conclude that also this is a genetic factor.
Third thing is my erectile dysfunction in migriane periods and prodrome period. Usually I have no problems with this, but when migraine is coming close, then I loosing my sensitivity and erection stability.
So I decided to take a look at possible reasons of all these problems as they all are related to neurons and vessels and there is one thing that may be the same for all these issues, and it's CGRP (calcitonin gene-related peptide), which antagonists are used to threat migraine. I did not find any researches in this theme, but for me it looks so logical. This peptide works as immune system in neirons where herpes sits, so I conclude that my CDRP system is not working well, but what I cannot understand is, that why migraine is affecting my erection, because as I understand, then migraine conditions leads to expanded vessels, what should make opposite effect. Also I read that CDRP antagonist medicine is blocking there receptors what means that blood vessels are not expanding and erection should become worse, but they do not say that these drugs have such side effect (I do not use these drugs). So this is what I'd like to discuss, maybe someone has any biochemists or know nay forums where this thing can be discussed?