From taking a look at their website, it appears these patches have a combination of ginger, butterbur and ashwanga. These are various ingredients that others have used to help manage migraine and chronic pain/nausea. While we don't have any feedback from our community on the actual patches- we have heard that these ingredients are ones that some community members take (as supplements) to assist with the management and treatment of migraine. Hope that helps. Warmly, Holly (migraine.com team).