I rarely see literature or discussions about collagen so I want your input here. Bone, skin, hair, and even the GI tract share collagen I as a key building block. I've been on the medication three years, and recently decided to go off of it.
Collagen holds up our skin like little pillars. This way it keeps it structure and stays plump. It starts to decline around 30 at a rate of 1-2% per year. If you add stress, sun exposure and smoking, that can increase the normal decline.
I used to have very full cheeks. Even when I lost modest weight, they were plump and healthy. But now, my cheeks have fallen. They have no structure: my derm said I have collagen loss.
Instead of losing about 1-2% collagen per year as is "normal" (so 6-7% in 3 years) I feel I've lost 15% since being on topamax.
Has anyone else experienced more wrinkles or collagen loss in the face? Also, my derm said that ANY medication where your body must "adjust" (e.g. noticeable side effects) can inherently damage collagen. Also, bone loss is listed as a SE in topamax, and it's primary building block is collagen! I'd love to hear people's story if they are willing to share. Thanks!