What Are CGRP Inhibitors?...CGRP-targeting mAbs block the key from hitting the lock, either by binding to CGRP (the key) or to the CGRP receptor (the lock)....
Aimovig (erenumab-aooe)...This stops CGRP from binding to the receptors in sensory nerves, thus stopping migraine attacks that were started by CGRP....
CGRP Treatments: No Happy Ending Yet...Before CGRP (brand name), I had 14 migraines a month. After two months of CGRP (brand name), now I have 25+ a month.”...reactions49comments
How CGRPs for Cluster Headache Differ from Migraine Disease...The biggest problem was the type of CGRP injectable medication....reactions11comments
Why Some CGRPs Work When Others Don't...Emgality and Ajovy attach to the CGRP protein (the key), while Aimovig works differently by blocking the CGRP receptor (the lock)....reactions125comments
Zavzpret™ (zavegepant)...Zavzpret is a CGRP receptor antagonist (also called a CGRP blocker). It works by blocking the CGRP receptors....
CGRP: 5 Essentials to Know...Here are five essential facts you need to know about CGRP: CGRP is a small protein that acts as a neurotransmitter (a chemical messenger) that is found...reactions15comments
Qulipta (atogepant)...Gepants work by blocking CGRP from attaching to its receptor. This prevents CGRP from initiating a pain signal....
CGRP and More: Treating Trigeminal Nerve Dysfunction...Gepants bind to the CGRP receptor, which prevents CGRP from binding to it....reactions10comments
Vyepti (eptinezumab-jjmr)...Vyepti is a monoclonal antibody that targets and blocks CGRP in the brain. CGRP is a protein found in these areas that transmits pain signals. ...
CGRP Gepants...Gepants work by blocking CGRP from attaching to its receptor. This prevents CGRP from initiating a pain signal....reactions6comments
Is Vyepti Raising My Blood Sugar?...CGRP has many benefits for your body. The CGRP antagonists prevent the available CGRP in our bodies from doing its typical job....reactions2comments
Will Botox Work For You? New Study May Provide a Clue...Participants whose CGRP levels were above 72 pg/ml were 28 times more likely to respond positively to Botox treatment than participants whose CGRP levels...reactions19comments
Treatment Options for Episodic vs. Chronic Migraine...by mouth.Anti-CGRP monoclonal antibodies – taken as injections – include: Small molecule CGRP inhibitors – taken orally – include: The same drugs...
CGRP Treatments: The Success Stories...I'm wondering if I should talk to my doc about either switching from one CGRP to another CGRP."...reactions10comments
Shout Out for Good Mainstream Media Coverage of Migraine Research...CGRP stands for calcitonin gene-related peptide. CGRP is found throughout the central and peripheral nervous systems....reactions4comments
Ubrelvy (ubrogepant)...A gepant is a small molecule designed to stop the action of CGRP. By blocking CGRP, pain perception may be reduced....
Are CGRPs Right for Me?...We've created a downloadable list of questions you can ask your doctor to see if you're a good candidate for CGRP gepants (acute treatment) or CGRP monoclonal...reactions5comments
Trying Oral Preventives That Target CGRP...I’m so glad my doctor urged me to consider oral preventives that target CGRP....reactions5comments
