So good to see you!!! I don't know if I would say "most" people. But it is common for some to have their medications stop working. Of course, everybody is different, and we all respond to medication in unique ways. So while the phenomenon is definitely something to be aware of as a possibility, try not to worry about it, because we really don't know what could change over time. I hope that makes sense. How are you doing? Sending big hugs your way!! Always here for you. -Melissa, team member