So often when you are on a specific treatment after a few months or maybe a year, the effects seem to wane. I'm 63 and this has been my experience my entire life. I'm very grateful for new and improved medication though I am concerned with long-term effects of so many of these cgrps because they haven't been around for very long. Some times it feels somewhat like a guinea pig. So we press on and Hope that there will be that treatment that will be effective in lasting